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| Study on Pathogenic Bacteria and Infection Risk Factors in 115 Patients with Suppurative Keratitis |
| Lu Xiaohuan |
| Clinical Laberatory,Xuchang Hospital,Xuchang 461000,China |
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Abstract Objective To analyze the pathogenic bacteria and risk factors of infection in patients with purulent keratitis.Methods A total of 115 patients with purulent keratitis were selected,their clinical data were collected,pathogenic examinations,drug resistance analysis,and risk factors for infection were analyzed.Results The main pathogenic bacteria in 115 patients with purulent keratitis were gram-positive bacteria.Among the main gram-positive bacteria,Staphylococcus epidermidis was highly resistant to ampicillin,piperacillin and erythromycin,and streptococcus hemolyticus was resistant to ampicillin.Pseudomonas aeruginosa,which is the main gram-negative bacteria,is highly resistant to ampicillin and erythromycin.Multi-factor analysis found that the history of eye surgery,wearing contact lenses,Ocular surface disease,use of antibacterial drugs,eye trauma or corneal foreign body,TC≤4.31mmol/L,WBC>6.67×109/L,ALB≤39.21g/L,Hb≤134.87g/L,CRP≥1.18mg/L All are risk factors for infection in patients with purulent keratitis（P<0.05）.Conclusion History of eye surgery,wearing contact lenses,ocular surface diseases,use of antibiotics,ocular trauma or corneal foreign bodies are risk factors for patients with purulent keratitis;the main pathogenic bacteria in patients with purulent keratitis are gram-positive bacteria,And the bacteria have the problem of multi-drug resistance,the clinic should choose sensitive drugs based on the results of drug susceptibility tests to reduce the migration of bacteria.
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Received: 24 February 2022
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[1] 蔡璇,李娟,施金玲,等.综合性医院眼科感染病原菌分布特征及耐药性分析[J].国际眼科杂志,2017,17(3):583-586.
[2] 陈耀升,王娟,张慧芝.368株临床常见病原菌的分布及其对抗菌药物的耐药性分析[J].抗感染药学,2020,17(6):809-812.
[3] 段虎成,陈瑞.某医院2017—2018年眼科感染病原菌分布及耐药性分析[J].传染病信息,2019,32(3):246-248.
[4] 胡晓丹,李思源,张阳,等.环孢素滴眼液联合抗感染治疗中重度化脓性角膜炎的临床疗效[J].眼科,2020,29(6):431-437.
[5] 赵见敏,骆阳,骆晔,等.感染性角膜炎的流行病学特征及临床病理探析[J].现代实用医学,2020,32(10):1240-1241,封4.
[6] 胡卫萍,徐永根,倪利洋,等.细菌性角膜炎951例病原学及药物敏感性分析[J].眼科新进展,2019,39(10):976-979.
[7] 刘雅萌,胡迭,姜涛,等.细菌性角膜炎362例病原学分析[J].精准医学杂志,2021,36(3):251-253,257.
[8] 包兴旺,杜新华,陆滨,等.真菌性角膜炎病原学及药敏结果分析[J].中华医院感染学杂志,2018,28(5):746-748.
[9] 郭楠,韩雪,陆成伟,等.真菌性角膜炎诊断学的研究进展[J].中国实验诊断学,2018,22(11):2022-2027.
[10] 王兵,王洪亮.南阳地区学龄前儿童感染性眼病病原菌分布及耐药性分析[J].国际眼科杂志,2019,19(7):1235-1238.
[11] 姜黎,周柯晶,刘惠娇,等.化脓性角膜炎患者病原菌与耐药性分析[J].中华医院感染学杂志,2017,27(15):3533-3536.
[12] 万磊,陈楠,张静,等.531例化脓性眼内炎患者的致病因素和病原学特征分析[J].中华眼底病杂志,2019,35(2):181-186. |
| [1] |
. [J]. journal1, 2023, 43(2): 86-88. |
| [2] |
Liu Junbo, Xu Hongying, Yang Limin. Analysis of the Incidence of Delirium and Related Factors in ICU Patients After General Anesthesia[J]. journal1, 2022, 42(5): 37-39. |
| [3] |
. [J]. journal1, 2022, 42(5): 64-65. |
| [4] |
Li Ning. Distribution of Pathogens and Laboratory Analysis in Patients With Chronic Obstructive Pulmonary Disease Combined With Ventilator-Associated Pneumonia[J]. journal1, 2022, 42(3): 4-6. |
| [5] |
Liu Yingxia, Huang Zhuoya, Zhong Ming, Chen Mingquan, Zhao Wenli. Analysis of the Difference Between Pathological Stage and Clinical Stage of Cervical Cancer and the Risk Factors Influencing Lymph Node Metastasis[J]. journal1, 2021, 41(3): 29-30. |
| [6] |
. [J]. journal1, 2021, 41(3): 53-54. |
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2023, Vol. 43 
