Abstract：The article discusses the importance of drug toxicity assessment and how to reduce drug toxicity through modifications of chemical structures.It details an experiment on the toxicity assessment of an anticancer drug（Bevacizumab）.The experiment used both animal models and cell culture methods to comprehensively evaluate the safety of Bevacizumab.The results showed that Bevacizumab exhibited certain toxicity to rats and human liver cell culture systems at high doses or concentrations.It is recommended that further drug development should involve optimization of chemical structures to reduce potential toxicity risks.This research not only provides important safety data for further drug development but also offers a comprehensive experimental model for drug toxicity assessment.
娄人介. Bevacizumab药物的毒性评估与安全性实验研究[J]. 哈尔滨医药, 2024, 44(3): 8-10.
Lou Renjie. Toxicity Assessment and Safety Experimental Study of the Drug Bevacizumab. journal1, 2024, 44(3): 8-10.
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