Abstract：Objective To examine the risk factors associated with lung cancer in individuals with chronic obstructive pulmonary disease(COPD)who also have emphysema. Methods A total of 318 patients with emphysema type COPD admitted to our hospital from June.According to the results of histopathological examination,they were divided into lung cancer group(33 cases)and non-lung cancer group(285 cases).The clinical data of the two groups were compared,and binary logistic regression analysis was used to screen the independent risk factors of emphysematous COPD complicated with lung cancer. Results The comparison of basic clinical data between two groups of COPD patients with emphysema showed that there were statistically significant differences in gender,age,smoking index,COPD duration,persistent chest pain,and hemoptysis between patients with concurrent lung cancer and those without concurrent lung cancer(P<0.05).The binary logistic regression analysis showed that age,smoking index,COPD duration,persistent chest pain,and hemoptysis are independent risk factors for pulmonary emphysema COPD complicated with lung cancer,which can increase the risk of concurrent lung cancer by 3.30 times,5.30 times,3.20 times,4.12 times,and 3.64 times,respectively(P<0.05). Conclusion Age,smoking index,COPD duration,persistent chest pain,and hemoptysis are independent risk factors for lung cancer in COPD with emphysema,which can increase the risk of lung cancer by 3.30 times,5.30 times,3.20 times,4.12 times,and 3.64 times,respectively.Therefore,comprehensive preventive measures should be taken,including quitting smoking,actively treating COPD,and regularly undergoing chest X-rays or CT scans,in order to reduce the risk of developing lung cancer and improve the quality of life of patients.
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2026, Vol. 46 
