Abstract：Objective To investigate the clinical effect of different doses of IVIG in the treatment of children with Kawasaki disease（KD）.Methods 40 children with KD were divided into two groups,20 cases in each group.The experimental group was treated with intravenous injection of 2g/kg IVIG,while the reference group was treated with intravenous injection of 1g/kg IVIG.Results The improvement time of fever,rash,lymphadenectasis,hand and foot swelling and mucosal congestion in the experimental group was less than that in the control group（P<0.05）;After treatment,WBC,PLT,CRP and ESR of the two groups were lower than those before treatment（P<0.05）;There was no significant difference in the incidence of WBC,PLT,CRP,ESR and CAL between the two groups after treatment（P>0.05）.Conclusion Daily use of 2g/kg IVIG in the treatment of children with KD can reduce fever in a short period of time,and has a positive effect on the disappearance of skin rash,improvement of mucosal congestion,and detumescence of hands and feet.
袁科龙, 刘语思, 刘仕娥, 刘柳苑. 小儿川崎病应用不同剂量丙种球蛋白治疗对患儿白细胞的影响及冠状动脉病变发生情况分析[J]. 哈尔滨医药, 2022, 42(3): 24-25.
Yuan Kelong, Liu Yusi, Liu Shie, Liu Liuyuan. Effect of Different Doses of Gamma Globulin on White Blood Cells and Incidence of Coronary Artery Disease in Children With Kawasaki Disease. journal1, 2022, 42(3): 24-25.
2022, Vol. 42 
