Diagnostic Significance of Multi-slice Spiral CT Angiography Combined with Serum Lipoprotein-a Testing for Preoperative Classification of Acute Aortic Dissection
Wang Gaojun, Yang Hongwei, Wang Dateng, Yang Ming
Department of Cardiovascular Surgery,First Affiliated Hospital of Nanyang Medical College,Nanyang,Henan 473000,China
Abstract：Objective To analyse the diagnostic significance of multi-slice spiral computed tomography angiography(CTA)combined with serum lipoprotein-a testing for preoperative classification of acute aortic dissection(AAD). Methods A retrosp-ective analysis was conducted on the clinical data of 92 AAD patients admitted to the Department of Cardiovascular Surgery,First Affiliated Hospital of Nanyang Medical College between January 2022 and December 2024.All patients underwent preoperative CTA and serum lipoprotein-a testing.Serum lipoprotein-a levels were compared across different Stanford classi-fications.Diagnostic outcomes and efficacy(sensitivity,specificity,accuracy)were evaluated for CTA,serum lipoprotein-a alone,and their combined use in classifying AAD. Results Surgical confirmation revealed 32(34.78%)Stanford Type A and 60(65.22%)Stanford Type B cases among the 92 patients.Serum lipoprotein-a levels were significantly higher in Stanford type A patients than in Stanford type B patients(P<0.05).No significant differences were observed in specificity or accuracy between CTA,combined CTA-lipoprotein-a diagnosis,and either modality alone(P>0.05).The diagnostic sensitivity of combined CTA and serum lipopro-tein-a was 96.88%(31/32),surpassing that of CTA alone(75.00%,24/32)and serum lipoprotein-a alone(59.38%,19/32)(P<0.05). Conclusion Combined CTA and serum lipoprotein-a testing effectively enhances the sensitivity of preoperative Stanford classification for AAD,providing reliable reference for early accurate classification and treatment planning in clinical practice.
王高俊, 杨宏伟, 王达腾, 杨明. 多排螺旋CT血管成像联合血清脂蛋白-a检测用于急性主动脉夹层术前分型的诊断意义[J]. 哈尔滨医药, 2026, 46(1): 31-33.
Wang Gaojun, Yang Hongwei, Wang Dateng, Yang Ming. Diagnostic Significance of Multi-slice Spiral CT Angiography Combined with Serum Lipoprotein-a Testing for Preoperative Classification of Acute Aortic Dissection. journal1, 2026, 46(1): 31-33.
2026, Vol. 46 
