Abstract:Cancer stem cells is a small cells group that could avoid radiotherapy and chemotherapy and has a strong self-renewal ability,it is a crucial reason for tumorigenesis,cancer progression,drug resistance and carcinoma palindromia,would be the principal way to cure cancers. PI3K/AKT is a significant signaling pathway correlated with cell proliferation and differentiation,which reported could modulate cancer stem cells self-renewal and fight off drug resistance caused by cancer stem cells,therefore,it is necessary to find out the relationship between PI3K/AKT pathway and cancer stem cells and explore a new way to cure cancers.
勾蓉. 肿瘤干细胞信号通路(PI3K/AKT)研究与进展[J]. 哈尔滨医药, 2021, 41(1): 139-141.
Gou Rong. Research and Development in the Signal Pathway of Cancer Stem Cells(PI3K/AKT). journal1, 2021, 41(1): 139-141.
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