Abstract：Objective To study the expression levels of TRAP1 and EGF in esophageal cancer,and to analyze the correlation between these two indexes and Clinicopathology. Methods 48 patients with esophageal cancer treated were included in the observation group;At the same time,48 healthy people were included as the control group.The levels of TRAP1 and EGF in the tissues of patients were detected by immunohistochemical method,and the correlation between these two indexes and clinical cases was analyzed. Results The positive rates of TRAP1 and EGF in the observation group were higher than those in the control group.There was a positive correlation between these two indexes and TNM stage,location,lymphatic metastasis and degree of differentiation in the observation group（P<0.05）. Conclusion The levels of TRAP1 and EGF in patients with esophageal cancer are significantly different from those in normal population,which can be used as an important index for the diagnosis of esophageal cancer.At the same time,the close correlation between these two indexes and Clinicopathology also provides a new basis for more scientific and reasonable treatment of esophageal cancer.
张翠芬, 王永峰, 张红鸽. TRAP1、EGF在食管癌中的表达水平及其与临床病理的关系研究[J]. 哈尔滨医药, 2022, 42(6): 46-47.
Zhang Cuifen, Wang Yongfeng, Zhang Hongge. Expression of Trap 1 and EGF in Esophageal Carcinoma and Their Relationship With Clinicopathology. journal1, 2022, 42(6): 46-47.
2022, Vol. 42 
