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Diagnostic Significance of Ambulatory Electrocardiography for Pediatric Kawasaki Disease Combined with Coronary Artery Injury |
Wu Hao, Wang Fang, Feng Wenwen |
Department of Electrocardiography,Zhengzhou Children's Hospital,Henan Provincial Children's Hospital,Zhengzhou,Henan 450018,China |
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Abstract Objective To investigate the diagnostic significance of dynamic electrocardiography(DCG)for pediatric Kawasaki disease(KD)combined with coronary artery injury(CAL). Methods We retrospectively analyzed 70 children with KD,all of whom underwent conventional electrocardiography(ECG)and DCG,and analyzed the diagnostic results,diagnostic efficacy,and predictive value of ECG and DCG using coronary arteriography as the“gold standard” and compared the detection rate of abnormalities between the two modalities.The diagnostic results,diagnostic efficacy and predictive value of ECG and DCG were analyzed,and the detection rate of abnormalities of the two examinations was compared. Results Among the 70 children with KD in our group,48 cases of combined CAL and 22 cases of uncomplicated CAL were demonstrated by coronary angiography;33 cases of combined CAL and 20 cases of uncomplicated CAL were demonstrated by ECG;47 cases of combined CAL and 21 cases of uncomplicated CAL were demonstrated by DCG.The sensitivity of DCG examination was 97.92%(47/48),the accuracy of 97.14%(68/70)was higher than ECG examination 68.75%(33/48)and 75.71%(53/70),and the leakage rate of 2.08%(1/48)was lower than ECG examination 31.25%(15/48)(P<0.05).The negative predictive value of DCG examination was higher in 95.45%(21/22)compared with that of ECG examination 57.14%(20/35)(P<0.05).The detection rate of DCG abnormality was higher in 97.92%(47/48)of children with KD combined with CAL than in 68.75%(33/48)of children with ECG examination,and the detection rate of ECG and DCG abnormality was higher in 97.92%(33/48)and 68.75%(47/48)of children with KD combined with CAL than in 9.09%(2/22)(4.55%),4.55%(1/22)higher(P<0.05). Conclusion DCG has high sensitivity and accuracy in the diagnosis of pediatric KD combined with CAL,and it can reduce the misdiagnosis rate and improve the negative predictive value,and it can accurately detect the abnormal conditions of the children,which can provide a reference basis for the clinical development of the treatment plan.
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Received: 08 February 2025
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