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| The Impact of Insulin Combined with Dietary Intervention Therapy on the Lipid Levels and the Incidence of Gestational Complications of Gestational Diabetes Mellitus Patients |
| Li Yuan, Deng Xuecong, Wang Mengge, Li Huanhuan, Li Jing, Tian Ling* |
| The Third People's Hospital of Bengbu,Anhui,Bengbu,233000,China |
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Abstract Objective To investigate the effects of insulin combined with dietary intervention on the treatment of gestational diabetes mellitus(GDM). Methods A total of 96 GDM patients were included and randomLy divided into two groups.The control group(n=48)received routine dietary intervention guidance,while the observation group(n=48)received insulin combined with dietary intervention.Blood glucose and lipid parameters were compared between the two groups before intervention and after 2 weeks of intervention.The differences in pregnancy-related complications were also compared. Results After 2 weeks of intervention,the observation group showed lower levels of fasting blood glucose(FBG),2-hour postprandial blood glucose(2hPG),glycated hemoglobin(HbA1c),total cholesterol(TC),triglycerides(TG),and low-density lipoprotein cholesterol(LDL-C)compared to the control group(P<0.05).Additionally,the high-density lipoprotein cholesterol(HDL-C)levels in the obser-vation group were significantly higher than those in the control group(P<0.05).The rate of pregnancy-related complications in the observation group was,significantly lower than the observed in the control group(P<0.05). Conclusion The use of insulin com-bined with dietary intervention demonstrates a significant improvement in glucose and lipid metabolism for GDM patients,effectively reducing the incidence of related complications,highlighting its clinical value.
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Received: 30 May 2025
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2025, Vol. 45 
