AbstractObjective To investigate the effects of Application of pyloric-vagus-preserving gastrectomy in early gastric cancer. Methods According to the principle of completely random,120 cases of early gastric cancer patients for surgical treatment in our hospital were randomly divided into DG group and PPG group.PPG group were given the pyloric-vagus-preserving gastre ctomy,and DG group were treated with conventional distal gastrectomy.To record food block and dumping syndrome and other complications occurrence of the two groups of patients after reflux;and respectively measuring body weight,serum albu-min,serum cholesterol,and other indicators of recovery and the occurrence of gall-stones of two groups of patient after 1 month,3 months,6 months,12 months,18 months and 24 months;periodic endoscopy,were observed in patients with esopha- gitis,gastritis and food residue retention occurrence;surgery after the patients were followed up for a period of five years,the two groups were observed and recorded five years after cancer recurrence and 5-year survival rate. Results ①Incidence of postoperative complications of PPG group were significantly lower than DG group,and the difference above was statistically significant（P<0.05）.②The incidence of gallstones with PPG group were significantly lower than DG group,and the above difference was statistically significant（P<0.05）.③Postoperative residual esopha- gitis and gastritis incidence of patients PPG group were 6.8%,28.9%,which all were lower than DG group of patients（8.1%,31.1%）;Food retention rate and the incidence of bile reflux of PPG group were 8.5% and 0.0% ,which all was significantly lower than DG group（19.7%,8.2%）,and above differences were statistically significant（P<0.05）.④DG postoperative 5-year recurrence rate was 6.6%,mainly in the submucosa carcinoma,5-year survival rate was 91.8%;PPG group tumor recurrence after five years was 5.1%,almost all of the submucosa carcinoma 5-year survival rate was 93.2%;but more than two groups showed no significant difference（P=0.72 recurrence rate,P5=0.61）. Conclusion pyloric-vagus-preserving gastrec-tomy in the clinical treatment of early gastric cancer can be effective in preventing re-flux,food block and dumping syndrome and other postoperative complications,gallstones and bile reflux occurs,and it has important clinical value in improving the patient's quality of life.
2023, Vol. 43 
