|
|
Effects of Non-invasive Ventilator Combined with Low-flow Oxygen Inhalation on Arterial Blood Gas in Elderly Patients with Acute Outbreak of COPD |
Zhang Xuejiao, Wang Jintao |
Department of Respiratory Medicine,Zhengzhou First People's Hospital,Zhengzhou 450052,Henan |
|
|
Abstract Objective To investigate the effect of non-invasive ventilator combined with low-flow oxygen inhalation on arterial blood gas in elderly patients with acute outbreak of chronic obstructive pulmonary disease(COPD). Methods A total of 80 elderly patients with COPD were selected and divided into two groups according to random envelope method,the control group(n=40 cases,low flow oxygen therapy)and the observation group(n=40 cases,low flow oxygen therapy + non-invasive ventilator ventilation therapy).The pulmonary function indexes,arterial blood gas indexes and hospitalization indexes of COPD patients before and 14 days after treatment were compared between the two groups. Results After 14 days of treatment,the FEV1,VC and PEF50 in the observation group were higher than those in the control group(P<0.05).After 14 days of treatment,the arterial blood pH of the observation group was no different from that of the control group(P>0.05),PaO2 was higher than that of the control group(P<0.05),and PaCO2 was lower than that of the control group(P<0.05).The total days of hospitalization and ICU stay in the observation group were less than those in the control group(P<0.05),and there was no difference in the intubation rate between the observation group and the control group(P>0.05). Conclusions Low-flow oxygen therapy combined with non-invasive ventilator ventilation in the treatment of elderly COPD patients can improve lung function,arterial blood gas,and reduce hospitalization days,and it is worthy of clinical promotion.
|
Received: 09 August 2022
|
|
|
|
|
[1] 刘印红,张勇,张扬,等.纳洛酮联合无创呼吸机对老年慢性阻塞性肺疾病合并呼吸衰竭患者血气指标、肺功能的影响[J].贵州医药,2016,40(5):486-488. [2] 老奋坚,舒宗妮,韩俊彦,等.白细胞介素-32在慢性阻塞性肺疾病发病中的研究现状[J].广东医学,2016,37(9):1395-1397. [3] 王凡. 无创正压通气治疗合并Ⅱ型呼吸衰竭的老年慢性阻塞性肺病急性加重患者的临床疗效及安全性分析[D].江苏:苏州大学,2018. [4] 齐晓伟. 基层医院慢性阻塞性肺病急性加重并肺动脉栓塞的临床分析[D].山东:青岛大学,2018. [5] 金晶. 益气固表丸治疗COPD合并SMD疗效观察及分子机制研究[D].新疆:新疆医科大学,2019. [6] 刘祖洪. 无创呼吸机通气联用乙酰半胱氨酸吸入治疗在伴有Ⅱ型呼吸衰竭慢性阻塞性肺疾病中的疗效观察[D].南昌大学(医学院),2020. [7] 郑一鸣. 哮喘缓解期患儿的心肺运动试验分析[D].辽宁:大连医科大学,2018. [8] 刘莉敏,李玉磊,李春,等.无创呼吸机治疗老年慢性阻塞性肺疾病急性加重呼吸衰竭的疗效及其对动脉血气的影响[J].中国老年学杂志,2020,40(9):1854-1856. [9] 张丹丹,张玲玲,刘剑南.老年COPD病人血清瘦素、抵抗素水平与呼吸中枢驱动指标的相关性[J].实用老年医学,2022,36(5):502-505. [10] 农凌波. 无创通气辅助下纤支镜经鼻气管插管有效性和安全性研究[D].广州医科大学,2017. [11] 刘春梅,王海龙,王迪.无创呼吸机与鼻导管吸氧对慢性阻塞性肺疾病急性加重呼吸衰竭患者疗效及动脉血气指标影响[J].中国急救复苏与灾害医学杂志,2021,16(7):766-768,777. [12] 邢乃姣. COPD合并呼吸衰竭应用无创呼吸机患者延续护理方案的构建及评价[D].山东:青岛大学,2019. [13] 李春艳. 远程监控调节家用无创呼吸机改善慢阻肺合并Ⅱ型呼吸衰竭患者症状有效性的研究[D].陆军军医大学,2021. [14] 韩利红. BiPAP无创呼吸机对重度COPD合并慢性呼吸衰竭患者的疗效分析[D].河南:郑州大学,2016. |
[1] |
. [J]. journal1, 2022, 42(6): 95-96. |
|
|
|
|