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| Effects of LNG-IUS and Dydrogesterone on Clinical Symptoms,Sex Hormones and Recurrence Rate in Patients with Endometrial Polyps after Transcervical Resection of Endometrial Polyps |
| Chen Rong |
| Department of Obstetrics and Gynecology,Fuqing Maternal and Child Health Hospital,Fuqing 350300,China |
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Abstract Objective To observe the effects of levonorgestrel-releasing intrauterine system(LNG-IUS)and dydrogesterone on clinical symptoms,sex hormone levels and recurrence rate in patients with endometrial polyps(EP)after transcervical resection of endometrial polyps(TCRP). Methods A total of 90 EP patients admitted to our hospital from August,all of whom underwent TCRP.They were divided into the control group(treated with oral dydrogesterone after surgery)and the observation group(treated with postoperative LNG-IUS placement)by random number table method,with 45 cases in each group.The clinical symptoms,endometrial thickness,sex hormone levels,systemic adverse reactions and recurrence rate were observed and compared between the two groups. Results After treatment,the menstrual volume and menstrual days in the observation group were less than those in the control group,and the endometrial thickness was lower than that in the control group(P<0.05).The serum levels of luteinizing hormone(LH),estradiol(E2),progesterone(P)and follicle-stimulating hormone(FSH)in the observation group were all lower than those in the control group(P<0.05). Conclusion There was no significant difference in the incidence of systemic adverse reactions between the two groups(P>0.05).The recurrence rate of the observation group was lower than that of the control group(P<0.05).
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Received: 06 February 2026
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[1] 李娟,韩文晖,叶佳佳.雌二醇/雌二醇地屈孕酮在子宫内膜息肉宫腔镜切除术后患者中的应用[J].中国药物应用与监测,2025,22(5):865-868. [2] 曹龙梅,计恩然,邹冰冰.炔雌醇环丙孕酮片联合宫腔镜病灶电切术治疗子宫内膜息肉伴异常子宫出血的疗效[J].临床和实验医学杂志,2025,24(8):859-863. [3] 杨海霞,汪莹,刘丽丽,等.宫腔镜旋切术与宫腔镜电切术治疗子宫内膜息肉的疗效观察[J].临床和实验医学杂志,2025,24(11):1182-1186. [4] 梁学梅,闫颖.宫腔镜下子宫内膜息肉切除术后应用LNG-IUS对子宫内膜厚度及复发影响[J].中国计划生育学杂志,2023,31(11):2563-2567. [5] 杨晓红,倪春超,邬晨圆,等.曼月乐环、地屈孕酮片在子宫内膜息肉电切术后患者中的应用[J].药学进展,2025,49(9):769-773. [6] 谢幸,孔北华,段涛.妇产科学[M].9版.北京:人民卫生出版社,2018:307-309. [7] 马春晶,赵兴会,朱春燕,等.宫腔镜子宫内膜息肉切除术对子宫内膜息肉合并不孕患者复发率及远期妊娠率的影响[J].临床误诊误治,2023,36(4):78-81. [8] 赵一,侯颖,马雪莲.曼月乐与地屈孕酮预防子宫内膜息肉切除术后息肉复发的临床效果比较[J].分子诊断与治疗杂志,2025,17(10):1957-1959,1963. [9] 孙悦. LNG-IUS对子宫内膜息肉电切术病人雌孕激素、炎性因子及子宫内膜组织中IGF-Ⅰ及受体的影响[J].蚌埠医学院学报,2022,47(7):893-897. [10] 古衡芳,肖雁冰,赵菁,等.宫腔中放置LNG-IUS联合桂枝茯苓丸对年轻子宫内膜息肉切除术后患者的影响[J].西部中医药,2023,36(9):115-119. [11] 李璐,朱世丽,纪芬.地屈孕酮辅助宫腔镜子宫内膜息肉切除术治疗对患者子宫内膜厚度、VEGF水平及复发率的影响[J].临床误诊误治,2023,36(8):76-79. [12] 潘雯,刘素芬,张洪,等.地屈孕酮治疗子宫内膜息肉的临床效果[J].生殖医学杂志,2024,33(11):1503-1506. [13] 刘娟,闵丹,同慧莉.曼月乐对子宫内膜息肉电切除术后患者的性激素、炎症因子及复发状况的影响[J].海南医学,2022,33(21):2780-2783. |
| [1] |
. [J]. journal1, 2025, 45(5): 133-135. |
| [2] |
. [J]. journal1, 2025, 45(5): 109-111. |
| [3] |
Yu Tiantian, Feng Linna, Zhang Zigui. Effect of Hysteroscopic Electroresection on Ovarian Function and Total Antioxidant Capacity Levels in Patients with Endometrial Polyps[J]. journal1, 2025, 45(4): 35-39. |
| [4] |
. [J]. journal1, 2025, 45(2): 70-72. |
| [5] |
. [J]. journal1, 2025, 45(2): 110-112. |
| [6] |
. [J]. journal1, 2025, 45(1): 122-124. |
|
|
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