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| Clinical Efficacy of Glipizide Combined With Metformin Hydrochloride in the Treatment of Elderly Diabetes |
| Xie Weijia1, Huang Liming2, Huang Zhedan3 |
1. Department of Pharmacy,Beijing Street Community Health Service Center,Guangzhou 510030,China;
2. Inpatient Pharmacy,Guangzhou Women and Children Medical Center,Guangzhou 510000,China;
3. Department of Pharmacy,The Third Affiliated Hospital of Sun Yat sen University,Guangzhou 510630,China |
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Abstract Objective To explore the clinical efficacy of glipizide combined with metformin hydrochloride in the treatment of elderly diabetes.Methods Select 89 elderly diabetic patients from January 2019 to January 2020 were selected and divided into control group(n=49)and combination group(n=40)according to the random number table method.The control group was treated with glipizide,while the combination group was treated with metformin hydrochloride on the basis of the control group.The changes of blood glucose index,treatment effect and adverse reaction rate before and after treatment were compared between the two groups.Results After treatment,the FPG,2hFPG,HbA1c and FINS of the two groups were significantly lower than before treatment,and the above indicators of the combination group were lower than those of the control group(P<0.05);The total effective rate of the combined group was 92.5%,which was significantly higher than the 75.51% of the control group(P<0.05).Conclusion Glipizide combined with metformin hydrochloride in the treatment of elderly diabetic patients can effectively improve the blood glucose level,blood glucose control and therapeutic effects are better than glipizide alone.
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Received: 18 November 2020
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[1] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2017年版)[J].中国实用内科杂志,2018,38(4):292-344.
[2] 陈文明,卓名,李伟杰,等.格列齐特联合二甲双胍治疗老年2型糖尿病患者的效果[J].中华灾害救援医学,2020,8(5):259-262.
[3] 吕旭艳,谢敏,陈小丽.阿卡波糖与瑞格列奈联合二甲双胍治疗2型糖尿病餐后高血糖的效果观察[J].中国药师,2016,19(6):1113-1115.
[4] 刘丽楠,李敬华,王素莉,等.阿卡波糖联合格列吡嗪对初诊2型糖尿病患者血糖、血脂、胰岛功能与血清微小核糖核酸的影响[J].中国药房,2016,27(11):1527-1529.
[5] 宋英. 格列吡嗪联合盐酸二甲双胍治疗糖尿病的临床疗效探讨[J].中国全科医学,2017,20(S3):75-76. |
| [1] |
Wang Li. Correlation Between Serum Lp（a）,APN Levels and Renal Injury in Patients With Diabetic Nephropathy[J]. journal1, 2021, 41(5): 60-61. |
| [2] |
. [J]. journal1, 2021, 41(5): 96-97. |
| [3] |
. [J]. journal1, 2021, 41(5): 137-138. |
| [4] |
. [J]. journal1, 2021, 41(4): 49-50. |
| [5] |
. [J]. journal1, 2021, 41(3): 51-52. |
| [6] |
. [J]. journal1, 2021, 41(3): 126-126. |
|
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2021, Vol. 41 
