|
|
|
| Effects of Imipenem Combined With Ambroxol on the Levels of WBC,PCT and CRP in Patients With Severe Pneumonia |
| Yang Mingjie, Dai Dunlin, Yu Jun |
| First People's Hospital of Xinyang,Department of Comprehensive Intensive Medicine,Xinyang 464000,China |
|
|
|
|
Abstract Objective To explore the effects of imipenem combined with ambroxol on the levels of WBC,PCT and CRP in patients with severe pneumonia.Methods The clinical data of 80 patients with severe pneumonia admitted in our hospital from November 2018 to March 2020 were retrospectively analyzed and grouped according to different treatment plans.The patients treated with ambroxol were included in the control group(40 cases),and the patients treated with imipenem combined with ambroxol were included in the observation group(41 cases).Compare the symptoms improvement and mechanical ventilation time of the two groups.The WBC,PCT,CRP,arterial oxygen partial pressure(PaO2),and arterial carbon dioxide partial pressure(PaCO2) were compared between the two groups before treatment and after 14 days of treatment.Results The time for body temperature recovery and mechanical ventilation in the observation group was shorter than that in the control group,and the rate of lesion absorption was higher than that in the control group.The difference was statistically significant(P<0.05).Before treatment,there was no significant difference in WBC,PCT,CRP,PaO2,PaCO2 between the two groups(P>0.05).After 14 days of treatment,WBC,PCT,CRP,and PaCO2 in both groups were decreased,and PaO2 was increased,and the change in the observation group was greater,the difference was statistically significant(P<0.05).Conclusion The treatment of severe pneumonia patients with imipenem combined with ambroxol can accelerate the absorption of the lesions,reduce the inflammatory response,increase the blood oxygen content,and promote the patients' early recovery of health.
|
|
Received: 30 August 2020
|
|
|
|
|
|
[1] 符瑜,吴少敏,曾昭凡.乌司他丁联合胸腺肽对重症肺炎患者呼吸功能和炎症应激反应的影响[J].中国医药,2019,14(8):1159-1163.
[2] 濮雪华,揭红英,缪小莉,等.支气管肺泡灌洗对重症肺炎合并呼吸衰竭患者正五聚体蛋白-3水平的影响[J].中华老年多器官疾病杂志,2019,18(8):588-592.
[3] 张健,蔡江红,彭吾训.盐酸氨溴索联合纤维支气管镜吸痰对老年重症肺炎血气指标及安全性影响的Meta分析[J].中华医院感染学杂志,2019,29(23):3563-3568.
[4] 褚利红,张莎莎.解毒清肺汤联合西医常规治疗重症肺炎的疗效观察[J].中国中医药科技,2019,26(5):713-714.
[5] 张毓玲,赵世同,曹艳红,等.重症肺炎的中医证候研究及其与WBC、CRP、PCO2的关系[J].中国中医急症,2019,28(9):1622-1624.
[6] 蔡荣. 机械通气联合大剂量氨溴索治疗老年重症肺部感染患者的疗效及对血浆PCT、CRP水平的影响[J].河北医学,2019,25(6):965-969.
[7] 张杨,任悦,李丹丹,等.大剂量氨溴索治疗重症肺炎疗效及安全性的meta分析[J].中国医刊,2019,54(5):558-564.
[8] 隗世波,刘青云,钟群琼.纤维支气管镜联合氨溴索肺泡灌洗治疗重症肺炎伴肺不张的效果及对血清PCT和hs-CRP的影响[J].解放军医药杂志,219,31(9):26-30. |
| [1] |
Li Jingjing. Effect of Yiqi Tongmai Decoction on Cardiac Function and Inflammatory Response in Patients With Coronary Heart Disease and Heart Failure[J]. journal1, 2021, 41(4): 126-127. |
| [2] |
. [J]. journal1, 2021, 41(3): 86-87. |
| [3] |
Wang, Jing. Changes and Significance of Serum TGF beta 1,sIL-2R and Tumor Markers Before and After Radiotherapy in Patients With Hepatocellular Carcinoma[J]. journal1, 2021, 41(1): 22-24. |
| [4] |
Wang Yijin, Qin Guoping, Xu Jiashun. To Explore the Clinical Value of Acetylcysteine Combined with Ambroxol in the Treatment of Acute Episode of Chronic Obstructive Pulmonary Disease in the Elderly[J]. journal1, 2021, 41(1): 27-28. |
| [5] |
. [J]. journal1, 2021, 41(1): 99-99. |
|
|
|
|
2021, Vol. 41 
