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Application Analysis of Ulinastatin Combined With Azithromycin Sequential in Children With Mycoplasma Pneumoniae Pneumonia |
Chen Meizhen |
Southeast Central Hospital of Dongguan City,Dongguan 523721,China |
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Abstract Objective To explore the sequential application of ulinastatin combined with azithromycin in children with Mycoplasma pneumoniae pneumonia. Methods Eighty children with Mycoplasma pneumoniae pneumonia who were treated were selected as the research objects.According to the random number table method,they were divided into observation and control groups,with 40 cases in each group.The control group was given azithromycin on the basis of conventional treatment;the observation group was given ulinastatin combined with azithromycin on the basis of conventional treatment.The treatment effect,the length of time for symptom disappearance and complications of the two groups of children were compared and analyzed. Results After the corresponding treatment,the two groups achieved good therapeutic effects.Among them,the children who received the sequential combined treatment of ulinastatin and azithromycin had more significant effects and higher treatment efficiency(P<0.05).The clinical symptoms such as high body temperature,pulmonary rales,and cough in the combined sequential group were also better controlled,and the clinical symptoms disappeared in a short time(P<0.05),which is more conducive to the physical and mental health of the children.After treatment,the observation group compared with the control group had a lower incidence of complications,fewer types,higher safety,and easier clinical cure. Conclusion The combination of ulinastatin and azithromycin in children with Mycoplasma pneumoniae pneumonia can achieve better results,fewer complications,and higher safety.It is worthy of clinical promotion and use.
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Received: 09 June 2021
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[1] 张秀梅. 孟鲁司特钠联合阿奇霉素对肺炎支原体肺炎患儿血清CRP、免疫球蛋白水平的影响[J].河南医学研究,2019,28(2):278-280. [2] 陈智芳. 联合布地奈德,特布他林雾化吸入对儿童肺炎支原体肺炎的治疗探讨[J].江西医药,2018,53(3):251-252. [3] 王浩. 小儿肺炎支原体肺炎应用阿奇霉素联合脂溶性维生素治疗的临床效果观察[J].航空航天医学杂志,2018,29(6):728-730. [4] 王海燕. 甲泼尼龙联合阿奇霉素治疗肺炎支原体肺炎患儿的疗效观察[J].中国社区医师,2019,798(36):86-88. [5] Sawires H,Abdelaziz H,Ahmed HM,et al.Randomized controlled trial on immunomodulatory effects of azithromycin in children with steroid-dependent nephrotic syndrome[J].Pediatric Nephrology,2019,34(9):1591-1597. [6] 林弘睿,万乃君,钱艺,等.小儿肺热咳喘口服液联合阿奇霉素对肺炎支原体肺炎患儿肺功能和炎性因子的影响[J].现代生物医学进展,2019,19(17):77-80. [7] 张秀梅. 孟鲁司特钠联合阿奇霉素对肺炎支原体肺炎患儿血清CRP、免疫球蛋白水平的影响[J].河南医学研究,2019,28(2):278-280. [8] Amza A,Kadri B,Nassirou B,et al.Community-level association between clinical trachoma and ocular chlamydia infection after MASS azithromycin distribution in a mesoendemic region of niger[J].Ophthalmic Epidemiology,2019,21(4):1-7. [9] 费新,华亚军,潘伟,等.盐酸氨溴索联合阿奇霉素序贯疗法对支原体肺炎患儿细胞因子及共刺激分子的影响[J].蚌埠医学院学报,2018,43(2):185-188. [10] 陈咏芳,陈丽芳,赖馨.2016年10月-2017年9月深圳龙岗区肺炎支原体感染血清检测分析[J].江西医药,2019,54(1):76-77. [11] 赵小利. 痰热清注射液联合阿奇霉素对肺炎支原体肺炎患儿症状改善及不良反应的影响[J].医药与保健,2018,26(10):132-133. [12] 朱满堂,罗红梅.阿奇霉素与热毒宁序贯治疗儿童支原体肺炎效果及对血清炎性因子的影响[J].白求恩医学杂志,2018,16(1):101-103. [13] 衣兰霞,朱淑霞.清肺止咳定喘清膏联合阿奇霉素治疗支原体肺炎的临床疗效及对血清炎性因子的影响[J].国际免疫学杂志,2018,41(1):46-49. [14] 赵茜叶,侍苏杰,徐海燕,等.肺炎支原体肺炎患儿肺功能变化与慢性咳嗽的相关性[J].中华实用儿科临床杂志,2019,34(4):270-273. [15] 曹黎明,田野,唐珩,等.地塞米松注射液联合阿奇霉素片治疗难治性肺炎支原体肺炎患儿的临床研究[J].中国临床药理学杂志,2020,36(3):227-229. [16] 李静,王雪艳,王梦娟,等.米诺环素联合阿奇霉素对重症肺炎支原体肺炎患儿血清CRP、D-D及肺功能的影响[J].中国生化药物杂志,2017,37(8):102-105. |
[1] |
Qian Qing. Effect of CRRT combined with Ulinastatin on inflammatory state and renal function in patients with acute septic shock[J]. journal1, 2022, 42(2): 29-30. |
[2] |
Li Huan, Meng Gang. Effects of Sequential Therapy of Budesonide Combined With Azithromycin on Levels of Serum IFN-γ and MCP-4 in Children Patients With MPP[J]. journal1, 2021, 41(6): 25-27. |
[3] |
Cai Lixia. A Comparative Study of Effects of Standard Triple Therapy and Sequential Triple Therapy on the Levels of Serum Inflammatory Factors in Children Patients With Hp Infection[J]. journal1, 2021, 41(4): 19-20. |
[4] |
. [J]. journal1, 2021, 41(4): 68-69. |
[5] |
Wang Xiaofei, Wang Kaiping, Wang Yan. Observation on Effects of Azithromycin Combined With Gamma Globulin in the Treatment of Pertussis in Children[J]. journal1, 2021, 41(3): 33-34. |
[6] |
. [J]. journal1, 2021, 41(2): 93-94. |
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