89例薄层液基细胞学检查异常结果与组织病理学诊断结果的一致性对比分析

doi:10.3969/j.issn.1001-8131.2023.06.016

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摘要目的探究89例薄层液基细胞学（TCT）检查异常结果和组织病理学诊断结果的一致性。方法回顾性分析1113例女性TCT检查及组织病理学检查的临床资料, 分析TCT检查异常结果与组织病理学诊断结果的一致性。结果 89例TCT检查异常中, 40例非典型且不明确意义的鳞状细胞（ASC-US）, 8例非典型且不除外高度上皮病变的鳞状细胞（ASC-H）, 27例低度鳞状上皮内病变（LSIL）, 13例高度鳞状上皮内病变（HSIL）, 1例鳞状细胞癌（SCC）; TCT诊断SCC与病理诊断符合率为100.00%; TCT对HSIL诊断符合率76.92%, 比LSIL的40.74%高（P< 0.05）; TCT检查异常结果显示LSIL及以上阳性41例（46.07%）, 病理诊断阳性47例（52.81%）, 两者相比差异无统计学意义（P> 0.05）。结论 89例TCT检查异常结果与组织病理学诊断结果的一致性较高, TCT可作为宫颈病变诊断的有效补充方式。

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	王飞刚
	吕军鹏
	苗红艳

关键词 ：宫颈癌, 宫颈上皮内瘤变, 液基薄层细胞学, 组织病理学

Abstract：Objective To explore the consistency between the abnormal results of thin-layer liquid-based cytology（TCT）and histopathological diagnosis in 89 cases. Methods The clinical data of 1113 female patients examined by TCT and histopathology were retrospectively analyzed, and the consistency between abnormal results of TCT and histopathological diagnosis was analyzed. Results Among the 89 cases of abnormal TCT, 40 cases were atypical squamous cells（ASC-US）, 8 cases were atypical squamous cells（ASC-H）with high epithelial lesions, 27 cases were low-grade squamous intraepithelial lesions（LSIL）, 13 cases were high-grade squamous intraepithelial lesions（HSIL）and 1 case was squamous cell carcinoma（SCC）.The coincidence rate between TCT diagnosis of SCC and pathological diagnosis was 100.00%.The diagnostic coincidence rate of TCT for HSIL was 76.92%, which was higher than that of LSIL（40.74%, P< 0.05）.The abnormal results of TCT showed that 41 cases（46.07%）were positive for LSIL and above, and 47 cases（52.81%）were positive for pathological diagnosis.There was no difference between them（P> 0.05）. Conclusion The abnormal results of TCT in 89 cases are consistent with the histopathological diagnosis, and TCT can be used as an effective supplementary method for the diagnosis of cervical lesions.

Key words： cervical cancer Cervical intraepithelial neoplasia Liquid thin layer cytology histopathology

收稿日期: 2022-12-12

PACS:

R446.8

引用本文:

王飞刚, 吕军鹏, 苗红艳. 89例薄层液基细胞学检查异常结果与组织病理学诊断结果的一致性对比分析[J]. 哈尔滨医药, 2023, 43(6): 44-46.
Wang Feigang, Lu Junpeng, Miao Hongyan. Comparative Analysis of Consistency between Abnormal Results of Thin-layer Liquid-based Cytology and Histopathological Diagnosis in 89 cases. journal1, 2023, 43(6): 44-46.

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