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Quick Search     Adv Search 2026 Vol. 46, No. 4 Published: 2026-08-25 1 Application of Combined Detection of Serum SAA,CRP and NLR Levels in the Prognostic Evaluation of Patients with Bacterial Pneumonia in the Short Term Wang Yiting, Lin Shenghua DOI: 10.3969/j.issn.1001-8131.2026.04.001 Objective To explore the value of combined detection of serum neutrophil-to-lymphocyte ratio(NLR),C-reactive protein(CRP),and serum amyloid A(SAA) in the short-term prognosis assessment of patients with bacterial pneumonia. Methods The clinical data of 86 confirmed patients were retrospectively analyzed and divided into a good prognosis group(71 cases) and a poor prognosis group(15 cases) based on prognosis.Patient data and laboratory test indicators were collected.Multivariate Logistic regression analysis was used to screen independent risk factors,and receiver operating characteristic(ROC) curves were drawn to evaluate the predictive efficacy of each indicator alone and in combination. Results The levels of serum NLR,CRP,and SAA in the poor prognosis group were significantly higher than those in the good prognosis group(P<0.05).Multivariate regression analysis showed that long hospital stay,high NLR,high CRP and high SAA were independent risk factors for poor short-term prognosis(P<0.05).ROC curve analysis indicated that the AUC of the combined prediction of NLR,CRP,and SAA was 0.963,with a sensitivity of 91.2%,which was higher than that of individual indicator detection. Conclusion Serum NLR,CRP and SAA levels are effective indicators for the short-term prognosis assessment of bacterial pneumonia.The combined detection of the three can significantly improve the predictive efficacy and provide a reference for early identification of high-risk patients and optimization of clinical intervention strategies. 2026 Vol. 46 (4): 1-4 [Abstract] ( 111 ) HTML (1 KB)  PDF (605 KB)  ( 22 ) 4 Efficacy and Safety of Negative Pressure Closed Drainage and Ilizarov Bone Handling Technique for Traumatic Osteomyelitis Zhang Ya, Du Tingting DOI: 10.3969/j.issn.1001-8131.2026.04.002 Objective Contrare the efficacy and safety of different surgical modalities for traumatic osteomyelitis. Methods Selected 160 patients with traumatic osteomyelitis admitted to our hospital from June 2024 to June 2025,divided technique,drainage technique,Ilizarov bone handling technique,and negative pressure closed drainage;the changes of inflammatory factors,AOFAS score and Iowa knee score were detected,and the incidence of complications and clinical efficacy were evaluated. Results AOFAS score,and Iowa knee score were higher in the drainage group(P<0.05);TNF- α,CRP levels were decreased,and statistically significant(P<0.05). Conclusion The effect of negative pressure sealing drainage is better than that of Ilizarov bone handling technology,which can effectively reduce the occurrence of complications and promote rapid postoperative recovery.However,fewer pathological samples in this paper are included,which leads to some limitations in the study,and further increasing the sample size is needed to confirm the multi-center study. 2026 Vol. 46 (4): 4-7 [Abstract] ( 144 ) HTML (1 KB)  PDF (550 KB)  ( 12 ) 8 An Epidemiological Survey Study on Allergens in Patients with Allergic Diseases Hu Bin, Tan Yunning, Xin Xiaoqian, Li Zhen'an DOI: 10.3969/j.issn.1001-8131.2026.04.003 Objective To define the allergen profile and compare the efficacy of skin prick test(SPT) and serum specific IgE(sIgE) detection in allergic patients in Foshan. Methods From January 2023 to June 2024,121 allergic rhinitis patients from a Foshan hospital were enrolled.Data were collected via questionnaires.SPT and serum sIgE tests were performed. Results The top three allergens by SPT positivity were house dust mite(49.59%),German cockroach(25.62%),and poplar pollen(19.0%).By sIgE,they were house dust mite(42.98%),dust mite(20.66%),and cat dander(8.26%).For five common allergens,agreement between methods was good(71.90%~97.52%),but SPT had higher positivity rates(P<0.05).Total positivity did not differ by age,sex,or residence.However,among urban patients,those living ≥4 floors had higher positivity than those on 1-3 floors(96.00% vs 88.00%,P<0.05). Conclusion The main allergens in Foshan are house dust mite,German cockroach,and local tree pollens. 2026 Vol. 46 (4): 8-10 [Abstract] ( 105 ) HTML (1 KB)  PDF (425 KB)  ( 15 ) 11 Study on the Molecular Expression of PI3K/AKT Pathway and Insulin Sensitivity in Polycystic Ovary Syndrome Dong Lei, Xu Quanxiao, Wang Bo, Xu Fangfang DOI: 10.3969/j.issn.1001-8131.2026.04.004 Objective To investigate the correlation between the molecular expression of the PI3K/AKT signaling pathway and insulin sensitivity in patients with polycystic ovary syndrome(PCOS). Methods Sixty PCOS patients who visited our hospital from January 2024 to January 2025 were selected as the PCOS group,and 30 healthy women who underwent physical examinations during the same period were selected as the control group.The differences in the protein and mRNA expression levels of key molecules in the PI3K/AKT pathway(PI3K,AKT,insulin receptor substrate-1(IRS-1),and GLUT4) in peripheral blood mononuclear cells were detected and compared between the two groups.Pearson correlation analysis was used to analyze the correlation between the molecular expression level of the PI3K/AKT pathway and insulin sensitivity indicators. Results Patients in the PCOS group had higher FBG,2hPG,FINS,and HOMA-IR than the control group,while their ISI and glucose uptake were lower(P<0.05).The protein and mRNA expression levels of PI3K,AKT,IRS-1,and GLUT4 in the PCOS group were lower than those in the control group(P<0.05).The protein and mRNA expression levels of PI3K,AKT,IRS-1,and GLUT4 were positively correlated with glucose uptake and ISI(P<0.05),and negatively correlated with HOMA-IR(P<0.05). Conclusion Downregulation of PI3K/AKT pathway molecules in ovarian granulosa cells of PCOS patients is closely related to insulin resistance. 2026 Vol. 46 (4): 11-13 [Abstract] ( 89 ) HTML (1 KB)  PDF (424 KB)  ( 15 ) 14 Role of Mycobacterium Tuberculosis DNA Detection in Paraffin Tissue in Tuberculosis Screening Chen Huiqin, Zheng Jie DOI: 10.3969/j.issn.1001-8131.2026.04.005 Objective To analyze the clinical value of real-time fluorescent quantitative PCR(FQ-PCR) for detection of Mycobacterium tuberculosis(MTB) DNA in paraffin tissue in screening tuberculosis(TB). Method 118 TB patients admitted to our hospital from January 2017 to December 2019 were selected,and tissue specimens were collected,embedded in paraffin,and subjected to pathological examination;Furthermore,FQ-PCR and acid fast staining of tissue sections were used to detect MTB-DNA,and the positive detection rates of the three methods were compared. Result Among the paraffin embedded tissues of 118 selected patients,FQ-PCR,acid fast staining,and histopathological methods were used to detect MTB positivity in 70,50,and 65 cases,respectively,with positive rates of 59.32%,42.37%,and 55.08%,respectively.The positive rates of the three methods were significantly different(P<0.05).Compared with the acid fast staining method,the positive detection rate of MTB in lung,pleural,lymph node biopsy,and other tissue specimens is higher,FQ-PCR、 The histopathological method showed higher detection rates(P<0.05),while the positive detection rate of FQ-PCR in lung biopsy specimens was higher than that of histopathological method(P<0.05). Conclusion The use of FQ-PCR for detecting MTB-DNA in paraffin tissue is more effective than acid fast staining and tissue pathology methods in lung biopsy.It can be used as an important tool for screening TB and provide support for tissue pathology diagnosis. 2026 Vol. 46 (4): 14-16 [Abstract] ( 99 ) HTML (1 KB)  PDF (424 KB)  ( 13 ) 17 Efficacy of Vacuum-assisted Minimally Invasive Rotational Excision for Benign Breast Tumors under Ultrasound and Its Effect on Tumor Markers Wu Yun DOI: 10.3969/j.issn.1001-8131.2026.04.006 Objective to investigate the effect of vacuum-assisted minimally invasive rotary excision(VAB) under ultrasound in the treatment of benign breast tumors. Methods 80 patients with benign breast tumors treated in our hospital from July 2020 to June 2023 were selected and divided into 40 cases each in the control group(open surgery) and the study group(VAB) by applying the method of random number table,comparing the surgical indexes,pain factors [Neuropeptide Y(NPY),5-Hydroxytryptophan(5-HT),Prostaglandin E2(PGE2)],Visual Analog Scale(VAS) score,tumor markers [carcinoembryonic antigen(CEA),glycan antigen 125(CA125)],and complications. Results Surgical time,incision length,and bleeding were lower in the study group than in the control group,and the differences were statistically significant(P<0.05).Preoperatively,the difference between the two pain factors was not statistically significant(P>0.05);3d postoperatively,NPY,5-HT,and PGE2 were elevated in both groups,and NPY,5-HT,and PGE2 were higher in the control group than in the study group,with statistically significant differences(P<0.05).Postoperatively,VAS was lower in the study group than in the control group in 1d,3d and 7d,and the difference was statistically significant(P<0.05).Preoperatively,the difference between the two tumor markers was not statistically significant(P>0.05);postoperatively,CEA and CA125 were reduced in both groups,and the difference was statistically significant(P<0.05);the difference in CEA and CA125 between the groups was not statistically significant(P>0.05).Complications in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05). Conclusion Benign breast tumors treated with VAB can reduce the degree of pain,promote recovery,and have no effect on tumor markers. 2026 Vol. 46 (4): 17-19 [Abstract] ( 68 ) HTML (1 KB)  PDF (403 KB)  ( 12 ) 20 Effects of Estradiol Valerate Pretreatment on Cervical Endometrial Receptivity and Vaginal Microecology in Postmenopausal Women undergoing Cervical Cerclage Sun Hongxian DOI: 10.3969/j.issn.1001-8131.2026.04.007 Objective To investigate the effects of estradiol valerate pretreatment on cervical endometrial receptivity and vaginal microbiota in postmenopausal women undergoing intrauterine device(IUD)removal. Methods A total of 200 postmenopausal women requiring IUD removal admitted to our hospital from January 2021 to December 2025 were selected as clinical subjects.They were randomly divided into groups using a random number table.The control group(n=100) received no preoperative drug intervention,while the observation group(n=100) received estradiol valerate pretreatment.Clinical outcomes,IUD removal success rate,cervical endometrial receptivity,and vaginal microbiota were compared between the two groups. Results The observation group showed shorter cervical canal length,lower PI and RI,and higher cervical os dilation compared to the control group(P<0.05).The observation group also exhibited thicker endometrial thickness,larger endometrial volume,and higher VI,FI,and VFI(P<0.05).The observation group had lower pH,IL-6,and TNF-α levels,as well as higher relative abundance of Lactobacillus vaginalis(P<0.05).The observation group required shorter surgical time and had less intraoperative bleeding(P<0.05).The IUD removal success rate in the observation group was 97.00%,significantly higher than that in the control group(P<0.05).The complication rate in the observation group was 3.00%,significantly lower than that in the control group(P<0.05). Conclusion Estradiol valerate pretreatment before IUD removal in postmenopausal women can effectively improve surgical success rates,enhance cervical endometrial receptivity,and restore vaginal microbiota balance,demonstrating favorable clinical outcomes and high application value.It has high clinical application value. 2026 Vol. 46 (4): 20-22 [Abstract] ( 77 ) HTML (1 KB)  PDF (433 KB)  ( 16 ) 23 A Study on the Long-term Effects and Related Factors of Adjuvant Chemotherapy after Surgery in Patients with Stage IB-IIA Cervical Cancer and Recurrence Risk Factors Zhou Tong, Dong Guoling, Ma Qimin DOI: 10.3969/j.issn.1001-8131.2026.04.008 Objective To investigate the long-term efficacy of adjuvant chemotherapy after surgery in patients with stage IB-IIA cervical cancer and potential risk factors for recurrence,and to analyze the prognostic factors. Methods A retrospective analysis was conducted on the data of 162 patients with stage IB-IIA cervical cancer and potential risk factors for recurrence admitted to our hospital from January 2019 to January 2022.All patients underwent radical hysterectomy.Patients were divided into a chemotherapy group(n=89) and a control group(n=73) based on whether they received adjuvant chemotherapy after surgery.The chemotherapy group received adjuvant chemotherapy with paclitaxel combined with cisplatin,while the control group received only routine follow-up.A 3-year follow-up was conducted,and the progression-free survival(PFS) rate and overall survival(OS) rate of the two groups were recorded in detail.Logistic regression analysis was used to explore the relevant factors affecting the long-term prognosis of the patients. Results After 3 years of follow-up,the PFS rate in the chemotherapy group was 84.27%(75/89),and the OS rate was 87.60%(78/89),while the PFS rate in the control group was 63.01%(46/73),and the OS rate was 75.34%(55/73).The 3-year PFS and OS rates in the chemotherapy group were significantly higher than those in the control group(P<0.05).Poorly differentiated tumors,lymph node metastasis,vascular invasion,and tumor diameter≥4cm were risk factors affecting the 3-year PFS and OS rates(P<0.05),while adjuvant chemotherapy after surgery was a protective factor. Conclusion For patients with stage IB-IIA cervical cancer and recurrence risk factors,adjuvant chemotherapy after surgery can significantly improve their long-term PFS and OS rates and improve prognosis.Furthermore,poor tumor differentiation,lymph node metastasis,vascular invasion,and tumor diameter affect the long-term prognosis of patients. 2026 Vol. 46 (4): 23-26 [Abstract] ( 77 ) HTML (1 KB)  PDF (502 KB)  ( 16 ) 26 Application of 3D-VIBE Dynamic Enhanced MRI Quantitative Parameter Combined Model in Differential Diagnosis of Epithelial Ovarian Cancer Xu Jingyuan, Liu Qiang, Zhao Aobo DOI: 10.3969/j.issn.1001-8131.2026.04.009 Objective To evaluate the efficacy of a combined 3D-VIBE dynamic contrast-enhanced MRI quantitative parameter model in the differential diagnosis of epithelial ovarian cancer. Methods A retrospective analysis was conducted on the clinical and imaging data of patients with pathologically confirmed epithelial ovarian tumors admitted to our hospital from January 2023 to December 2025.Based on pathological examination results,100 patients were divided into a benign epithelial ovarian tumor group(benign group,n=40) and an epithelial ovarian cancer group(malignant group,n=60).All patients underwent routine MRI and 3D-VIBE dynamic contrast-enhanced MRI scans preoperatively.Quantitative parameters were compared between the two groups,and a combined quantitative parameter model was constructed.Receiver operating characteristic(ROC) curves were plotted to evaluate the differential diagnostic efficacy of single quantitative parameters and the combined model. Results The levels of Ktrans,Kep,and MS in the malignant group were higher than those in the benign group,while the levels of TTP and Ve were lower in the malignant group(all P<0.05).Multivariate logistic regression analysis showed that the five quantitative parameters(Ktrans,Kep,Ve,MS,and TTP) were closely related to the incidence of epithelial ovarian cancer(P<0.05).ROC curve analysis showed that the AUCs for the combined diagnosis of epithelial ovarian cancer by the five parameters(Ktrans,Kep,Ve,MS,and TTP) were 0.548,0.716,0.825,0.774,and 0.904,respectively.Z-tests showed that the combined diagnostic efficacy was higher than that of the individual parameters(Z=7.753,12.656,2.992,4.229,and 23.212,all P<0.05). Conclusion The 3D-VIBE dynamic contrast-enhanced MRI quantitative parameter combined model(Ktrans,Kep,Ve,MS,TTP) can effectively integrate the diagnostic information of multiple quantitative parameters,which helps to improve the differential diagnosis efficacy between epithelial ovarian cancer and benign epithelial ovarian tumors.Its sensitivity and specificity are higher than those of single-parameter diagnosis. 2026 Vol. 46 (4): 26-29 [Abstract] ( 90 ) HTML (1 KB)  PDF (568 KB)  ( 19 ) 30 Clinical Efficacy and Adverse Reaction Analysis of Anti-infective Drugs Combined with Glucocorticoids in the Treatment of Children with Severe Pneumonia in Pediatric Emergency Xu Shan DOI: 10.3969/j.issn.1001-8131.2026.04.010 Objective To investigate the clinical efficacy and incidence of adverse reactions of anti-infective drugs combined with glucocorticoids in the treatment of children with severe pneumonia in pediatric emergency,and to provide a reference for optimizing clinical treatment regimens. Methods A total of 90 children with severe pneumonia admitted to the pediatric emergency department of our hospital from July 2025 to December were selected and randomly divided into the control group and the observation group with 45 cases in each group using a random number table method.The control group was treated with anti-infective drugs alone,while the observation group was treated with glucocorticoids on the basis of the control group.Both groups completed standardized treatment and follow-up.The disappearance time of clinical symptoms and signs,laboratory inflammatory indicators before and after treatment,absorption of pulmonary lesions,respiratory function indicators,clinical efficacy,length of hospital stay and incidence of adverse reactions were compared between the two groups. Results The disappearance time of fever,cough,dyspnea and absorption time of pulmonary rales in the observation group were significantly shorter than those in the control group(P<0.05).After treatment,the peripheral blood white blood cell count(WBC),C-reactive protein(CRP) and procalcitonin(PCT) in both groups were significantly lower than those before treatment,and the levels of each indicator in the observation group were significantly lower than those in the control group(P<0.05).The complete absorption rate of pulmonary lesions in the observation group(71.11%) was significantly higher than that in the control group(40.00%)(P<0.05).After treatment,the blood oxygen saturation(SpO2),forced vital capacity(FVC),forced expiratory volume in the first second(FEV1) and FEV1/FVC in the observation group were significantly better than those in the control group(P<0.05).The total clinical effective rate and clinical cure rate in the observation group were significantly higher than those in the control group(P<0.05),and the length of hospital stay was significantly shorter than that in the control group(P<0.05).The adverse reactions in both groups were mainly mild to moderate gastrointestinal reactions and electrolyte disturbances,with no severe adverse reactions occurred.There was no statistically significant difference in the total incidence of adverse reactions between the observation group(11.11%) and the control group(15.56%)(P>0.05). Conclusion Anti-infective drugs combined with glucocorticoids in the treatment of children with severe pneumonia in pediatric emergency can rapidly relieve clinical symptoms,effectively reduce inflammatory indicators,promote the absorption of pulmonary lesions and the recovery of respiratory function,improve clinical efficacy and shorten the length of hospital stay.Moreover,standardized medication does not increase the risk of adverse reactions with good medication safety,which is worthy of clinical promotion and application. 2026 Vol. 46 (4): 30-34 [Abstract] ( 70 ) HTML (1 KB)  PDF (681 KB)  ( 18 ) 35 Survey and Analysis of Perinatal Risk Factors and Outcomes in Hospitalized Preterm Infants in Southern Hainan Chen Qiuning DOI: 10.3969/j.issn.1001-8131.2026.04.011 Objective To explore the core perinatal risk factors and disease outcome analysis of hospitalized premature infants in Qiongnan region. Methods A retrospective cohort study was conducted,including 80 premature infants admitted to our hospital from December 2023 to February 2025.The mothers' pregnancy conditions,neonatal clinical characteristics,complications,and developmental outcomes up to the corrected age of 12 months were analyzed. Results 92.5%(74/80) of the mothers had at least one high-risk factor.The most significant high-risk factors were premature rupture of membranes in 23 cases(28.7%),gestational diabetes in 17 cases(21.2%),and gestational hypertension in 16 cases(20%).Low birth weight accounted for 90%(72/80),and respiratory system complications had the highest incidence(60.00%).The follow-up showed that 13.89%(10/72) of the children had early neurodevelopmental abnormalities.Multivariate analysis suggested that birth weight<1.5 kg,gestational age<32 weeks,maternal concurrent gestational hypertension,and gestational diabetes were independent risk factors for developmental abnormalities. Conclusion Gestational hypertension,diabetes,and premature rupture of membranes are the main high-risk factors for premature birth in Qiongnan region.Targeted perinatal management and systematic follow-up are necessary. 2026 Vol. 46 (4): 35-37 [Abstract] ( 82 ) HTML (1 KB)  PDF (404 KB)  ( 14 ) 38 The Effects of Different Types of Insulin on Blood Sugar Levels of Pregnant Women with Gestational Diabetes Li Fei, Xu Xianghong, Qiu Chunxia, Hou Meilian DOI: 10.3969/j.issn.1001-8131.2026.04.012 Objective To explore the changes in blood sugar levels of pregnant women with gestational diabetes mellitus after treatment with various types of insulin(including biosynthetic human insulin and aspart insulin). Methods Using the lottery method,62 pregnant women with gestational diabetes who were hospitalized at Guangzhou Tianhe District Maternal and Child Health Hospital from January 2021 to December 2025 were randomly divided into the control group(treated with biosynthetic human insulin,n=31) and the study group(treated with insulin aspart,n=31).The changes in the effects of the two groups,blood glucose-related indicators,the cycle of achieving blood glucose control,lipid metabolism levels,and adverse maternal and infant outcomes were evaluated. Results The overall clinical effective rates of the two groups showed a significant difference(P<0.05);compared with before treatment,the blood glucose-related indicators [fasting blood glucose(FPG),glycosylated hemoglobin(HbA1c),2-hour postprandial blood glucose(2hPG)]and lipid metabolism indicators [triglycerides(TG),total cholesterol(TC)]of the two groups after treatment were significantly decreased,and the decrease in the study group was better than that in the control group(P<0.05);while the levels of high-density lipoprotein cholesterol(HDL-C) in both groups showed an increase,and the increase level in the study group was significantly higher than that in the control group(P<0.05);the time for all indicators of FPG,2hPG,FPG and 2hPG to reach the standard in the study group was shorter than that in the control group(P<0.05);the incidence of adverse neonatal outcomes and adverse pregnancy outcomes in the study group was lower than that in the control group(P<0.05). Conclusion Compared with the use of biosynthetic human insulin,the aspart insulin treatment regimen is more effective for pregnant women with gestational diabetes.It demonstrates significant advantages in improving blood sugar control,regulating lipid metabolism,shortening the period to achieve blood sugar control,and improving the prognosis of both mothers and infants. 2026 Vol. 46 (4): 38-41 [Abstract] ( 77 ) HTML (1 KB)  PDF (576 KB)  ( 19 ) 41 Dynamic Monitoring of Coagulation Function and Individualized Blood Component Transfusion Strategy in Patients Undergoing Massive Transfusion Wang Yitong, Zhao Zilu, Lu Mingyang DOI: 10.3969/j.issn.1001-8131.2026.04.013 Objective To investigate the clinical value of individualized blood component transfusion guided by dynamic coagulation monitoring in patients undergoing massive transfusion. Methods A total of 82 severe trauma patients requiring massive transfusion admitted to our hospital from January 2023 to June 2025 were selected and randomly divided into an observation group and a control group using a random number table method,with 41 cases in each group.The control group received monitoring of routine coagulation parameters combined with a 1:1:1 ratio transfusion protocol,while the observation group received dynamic thromboelastography(TEG) monitoring combined with a goal-directed individualized transfusion strategy.Changes in coagulation parameters before transfusion and at 24h and 48 h after transfusion were compared between the two groups.The volume of blood components transfused,blood loss,incidence of transfusion-related adverse reactions,and 28-day mortality were recorded in both groups. Results At 24h after transfusion,prothrombin time(PT) and activated partial thromboplastin time(APTT) in the observation group were significantly lower than those in the control group,while fibrinogen(FIB) level was significantly higher(P<0.05).At 48h after transfusion,there was no statistically significant difference in coagulation parameters between the two groups(P>0.05).The volumes of frozen plasma(FFP) and platelet transfusions in the observation group were significantly lower than those in the control group(P<0.01),while there was no significant difference in red blood cell transfusion volume between the two groups(P>0.05).The 24h blood loss in the observation group was lower than that in the control group(P<0.05).The incidence of transfusion-associated circulatory overload in the observation group was lower than that in the control group(P<0.05),and there was no significant difference in 28-day mortality between the two groups(P>0.05). Conclusion The individualized blood component transfusion strategy based on dynamic TEG monitoring can more rapidly correct coagulation dysfunction in patients undergoing massive transfusion,reduce the volume of plasma and platelet transfusions,and decrease the risk of transfusion-associated circulatory overload,serving as an effective approach for achieving precision transfusion therapy. 2026 Vol. 46 (4): 41-44 [Abstract] ( 78 ) HTML (1 KB)  PDF (569 KB)  ( 17 ) 45 The Impact of Dexmedetomidine and Remifentanil Combined Anesthesia on Hemodynamics and Anesthetic Recovery in Patients Undergoing Laparoscopic Hysterectomy Xing Yanmin, Qin Yufeng DOI: 10.3969/j.issn.1001-8131.2026.04.014 Objective To observe the effects of remimazolam combined with remifentanil anesthesia on patients undergoing laparoscopic hysterectomy. Methods A total of 124 patients who underwent laparoscopic hysterectomy at Anyang Maternal and Child Health Hospital from August 2024 to September 2025 were selected and divided into a control group (62 cases,receiving propofol combined with remifentanil anesthesia)and an observation group(62 cases,receiving remimazolam combined with remifentanil anesthesia).The hemodynamics,quality of anesthesia recovery,inflammatory indicators,sedation scores,and postoperative complications were compared between the two groups. Results At 5 minutes post-induction(T1),there were no statistically significant differences in heart rate(HR) and mean arterial pressure(MAP) between the two groups(P>0.05).At the time of tracheal intubation(T2),5 minutes after pneumoperitoneum establishment(T3),5 minutes after pneumoperitoneum release(T4),and at tracheal extubation(T5),the HR and MAP in the observation group were significantly lower than those in the control group(P<0.05).The observation group exhibited shorter times for eye opening,extubation,and orientation recovery compared to the control group(P<0.05).At 24 hours postoperatively,the inflammatory levels in the observation group were significantly lower than those in the control group(P<0.05).At T5,5 minutes after extubation(T6),and 30 minutes after extubation(T7),the Ramsay Sedation Scale(RSS) in the observation group was significantly higher than that in the control group(P<0.05).The complication rates between the two groups were comparable(P>0.05). Conclusion The application of remimazolam combined with remifentanil anesthesia in laparoscopic hysterectomy can stabilize intraoperative hemodynamics,reduce inflammation induced by surgery,improve the quality of anesthesia recovery,and does not significantly increase the risk of postoperative complications. 2026 Vol. 46 (4): 45-47 [Abstract] ( 74 ) HTML (1 KB)  PDF (429 KB)  ( 8 ) 78 Practice and Analysis of the Drug Traceability Code Management System in Hospital Drug Warehouses Ruan Binbin, Chen Lu, Wu Mei, Chen Guanxu, Li Tianping DOI: 10.3969/j.issn.1001-8131.2026.04.025 Objective To explore the practical effect of drug warehouse implementation of "code scanning warehousing+traceability management" mode,and to provide reference for optimizing drug traceability management system. Methods Taking the hospital's drug warehouse as the research object,a comparative analysis was conducted on the data changes in three dimensions:warehousing efficiency,error rate,and traceability code data upload before and after the application of the drug traceability management system.A month-on-month analysis method was adopted for data evaluation. Results Compared with the traditional warehousing mode,the introduction of the drug traceability management system has significantly improved the efficiency of drug warehousing(P<0.05),greatly reduced the error rate of warehousing(P<0.05),and ensured the real-time and accuracy of the data upload of drug traceability codes and the issuance by pharmacists. Conclusion The application of the drug scanning code traceability management system optimizes the work process of the drug warehouse and significantly improves the information management level of the drug warehouse traceability system. 2026 Vol. 46 (4): 78-81 [Abstract] ( 82 ) HTML (1 KB)  PDF (685 KB)  ( 5 )

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