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哈尔滨医药  2021, Vol. 41 Issue (4): 126-127    
  中医/中西医结合 本期目录 | 过刊浏览 | 高级检索 |
益气通脉汤对冠心病心力衰竭患者心功能和炎性反应的影响
李静静
巩义市人民医院中药调剂室,河南 巩义 451200
Effect of Yiqi Tongmai Decoction on Cardiac Function and Inflammatory Response in Patients With Coronary Heart Disease and Heart Failure
Li Jingjing
TCM Dispensing Room,Gongyi people's Hospital,Gongyi 451200,China
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摘要 目的 分析益气通脉汤治疗冠心病心力衰竭(HF)患者心功能和炎性反应的影响。方法 选取冠心病HF患者186例,按随机数字表法分为中医组(n=93)与西医组(n=93),西医组予以常规西医治疗,在西医组用药基础上中医组予以益气通脉汤,对比两组疗效和治疗前后心功能[左心室射血分数(LVEF)、舒张末期左心室内径(LVEDD)]、血清炎性因子水平[白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]。结果 中医组总有效率94.62%,较西医组75.57%高(P<0.05);治疗后,中医组LVEF水平较西医组高,LVEDD水平较西医组低(P<0.05);治疗后,中医组血清IL-6、TNF-α水平较西医组低(P<0.05)。结论 在西医治疗冠心病HF患者基础上予以益气通脉汤效果显著,可减轻炎症反应,改善心功能。
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李静静
关键词 冠心病心力衰竭心功能白细胞介素-6肿瘤坏死因子-α益气通脉汤    
AbstractObjective To analyze the effect of Yiqi Tongmai Decoction on cardiac function and inflammatory response in patients with coronary heart disease and heart failure(HF).Methods 186 patients with HF were selected and randomly divided into traditional Chinese medicine group(n=93)and Western medicine group(n=93).The western medicine group was given conventional western medicine treatment,on the basis of the western medicine group,the Chinese medicine group was given Yiqi Tongmai Decoction.The efficacy and cardiac function(LVEF,LVEDD)and serum inflammatory factor levels(IL-6,TNF-α)before and after treatment were compared between the two groups.The efficacy and cardiac function(LVEF,LVEDD)and serum inflammatory factor levels(IL-6,TNF-α)before and after treatment were compared between the two groups.Results The total effective rate of TCM group was 94.62%(88/93)higher than that of Western medicine group(75.57% (70/93)(P<0.05);after treatment,LVEF level in TCM group was higher than that in western medicine group,LVEDd level was lower(P<0.05);after treatment,serum IL-6 and TNF - α levels in TCM group were lower than those in western medicine group(P<0.05).Conclusion On the basis of western medicine treatment of HF patients with coronary heart disease,Yiqi Tongmai Decoction has a significant effect,which can reduce inflammation and improve heart function.
Key wordsCoronary heart disease    Heart failure    Heart function    Interleukin-6    Tumor necrosis factor-α    Yiqi Tongmai Decoction
收稿日期: 2020-12-09     
PACS:  R541.6  
引用本文:   
李静静. 益气通脉汤对冠心病心力衰竭患者心功能和炎性反应的影响[J]. 哈尔滨医药, 2021, 41(4): 126-127.
Li Jingjing. Effect of Yiqi Tongmai Decoction on Cardiac Function and Inflammatory Response in Patients With Coronary Heart Disease and Heart Failure. journal1, 2021, 41(4): 126-127.
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