Analysis of the Characteristics of Pathogenic Bacteria and Their Drug Resistance in Adult Patients with Severe Community-acquired Pneumonia in the Emergency Department
Lü Chengtian, Yan Yongxin, Liu Shizhuan, Guan Yuanzhi, Zhou Ming
Abstract：Objective Investigating the pathogenic characteristics and antibiotic resistance analysis of severe community-acquired pneumonia(SCAP)in emergency adults,providing a basis for early empirical selection of antibiotics. Methods We collected 202 cases of SCAP patients in our hospital from July 2024 to October 2025,conducted sputum bacterial cultures for them,and performed drug sensitivity tests to understand the pathogenic bacteria in the patients and analyze their drug resistance situation. Results A total of 224 pathogens were detected in 202 patients,including 118 Gram-negative bacteria(52.68%),59 Gram-positive bacteria(26.34%),and 47 fungi(20.98%).Among the patients,Pseudomonas aeruginosa,Acinetobacter baumannii,and Klebsiella pneumoniae had a resistance rate of 0.00% to meropenem and imipenem,and showed relatively low resistance(<30.00%)to amikacin and cefoperazone-sulbactam.Among the patients,Streptococcus pneumoniae and Staphylococcus aureus had a resistance rate of 0.00% to vancomycin and teicoplanin,and showed relatively low resistance(<30.00%)to tetracycline,gentamicin,and levofloxacin. Conclusion In clinical practice,it is important to improve pathogen detection and drug sensitivity testing as early as possible,and to select antibiotics reasonably based on the Results of drug sensitivity testing.This is of great significance for reducing the mortality rate and improving the prognosis of emergency SCAP patients.However,this study has the limitation of limited sample size,and in the future,the sample size needs to be expanded to obtain data with higher levels of evidence.
吕成添, 严永欣, 刘世专, 关远志, 周明. 急诊成人重症社区获得性肺炎的病原菌特征及其耐药性分析[J]. 哈尔滨医药, 2026, 46(5): 13-15.
Lü Chengtian, Yan Yongxin, Liu Shizhuan, Guan Yuanzhi Zhou Ming. Analysis of the Characteristics of Pathogenic Bacteria and Their Drug Resistance in Adult Patients with Severe Community-acquired Pneumonia in the Emergency Department. journal1, 2026, 46(5): 13-15.
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2026, Vol. 46 
