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2021 Vol. 41, No. 2
Published: 2021-04-25
1
The Effect of Calcium Carbonate D
3
Granules on Improving Bone Mineral Density in Children with Nutritional Rickets and Its Adverse Reactions
Liu Minmin, Chen Rijin, Lv Weidong, Liao Cairong, Huang Zi
Objective
To investigate the effects and adverse reactions of calcium carbonate D
3
particles in improving bone mineral density in children with nutritional rickets.
Methods
The clinical data of 76 children with nutritional rickets admitted were retrospectively analyzed, and the children were divided into study group（n=35） and control group（n=31） according to treatment methods.The study group was treated with calcium carbonate D
3
particles, the control group was treated with calcium gluconate vitamin D
2
chewable tablets（II）,and were contiously treated for 12 weeks.The treatment effective rate, tibia bone density before and after treatment, and the adverse reactions ratebetween the two groups were compared.
Results
The treatment effective rate of in the study group was higher than that in the control group, and the after treatment tibia bone density level in the study group was also higher than that in the control group （
P
<0.05）.The after treatment tibia bone mineral density of the 2 groups were higher than those of before treatment（
P
<0.05）.There was no significant difference in the adverse reactions rate between the 2 groups（
P
>0.05）.
Conclusion
Calcium carbonate D
3
particles can effectively improve the bone density and therapeutic effect of children with nutritional rickets, which is safe and reliable.
2021 Vol. 41 (2): 1-2 [
Abstract
] (
133
)
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3
Effect and Prognosis of Different Doses of Alteplase in the Treatment of Acute Ischemic Stroke
Zhao Liukai
Objective
To observe the effects and prognosis of different doses of alteplase in the treatment of acute ischemic stroke.
Methods
A total of 162 patients with acute ischemic stroke were selected and divided into the control group（79 cases） and the experimental group（83 cases）.They were treated with alteplase at low doses（0.6 mg/kg） and conventional doses（0.9 mg/kg）.The results of quality of life（SS-QOL） and stroke scale（NIHSS） assessment, prognosis and adverse reaction rate were compared between the two groups.
Results
After treatment, the SS-QOL scores of the two groups increased, and the scores of the experimental group at 1 day and 12 weeks after discharge were significantly higher than those of the control group（
P
<0.05）.After treatment,the NIHSS scores of the two groups were reduced, and the scores of the experimental group at 1 day of treatment and 12 weeks after discharge were significantly lower than those of the control group（
P
<0.05）.The good prognosis rate in the experimental group was 80.72%, higher than that in the control group（65.82%）（
P<
0.05）.The adverse reaction rate in the experimental group was 4.81%, and the adverse reaction rate in the control group was 2.53%.There was no significant difference in comparison.
Conclusion
Conventional dose alteplase thrombolysis is effective in the treatment of patients with acute ischemic stroke.It can effectively improve the quality of life and nerve function, and with high safety.
2021 Vol. 41 (2): 3-4 [
Abstract
] (
158
)
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5
Analysis of the Influence Factors of Ischemic Re-Perfusion Injury in Direct PCI Therapy in Patients With Acute Myocardial Infarction
Tao Gongda
Objective
To investigate the influence factors of ischemic re-perfusion injury（MIRI） in patients with acute myocardial infarction（AMI） directly through coronary artery intervention therapy（PCI）, with the aim of further improving the effect of PCI treatment.
Methods
Retrospective analysis of clinical data on 100 AMI patients who received PCI,included MIRI patients in the MIRI group and the remaining patients in the non-MIRI group.Comparing the two groups of general data（age, medical history, infarction site, BMI index, etc.）, all possible risk factors for the occurrence of MIRI were included in the variables and assigned to them, and the factors that could have caused mirI influences in PCI were obtained by non-conditional logistic regression analysis.
Results
MirI 58 cases occurred in 100 patients, accounting for 58.00%（58/100）, and no MIRI42 cases, accounting for 42.00%（42/100）.58 cases of MIRI occurred were included in the MIRI group, 42 cases of non-MIRI occurred were included in the non-MIRI group, and the possible influence factors were incorporated into the variables and assigned to them, and the results of the non-conditional logistic regression analysis showed that the patient's chest pain to the IRA opened too early, hypotension and multiple lesions before refilling were the risk factors for the occurrence of MIRI in PCI（OR>1,
P
<0.05）.
Conclusion
Chest pain to IRA open edgy early, re-injection before low blood pressure and multiple lesions may increase the risk of MIRI in AMI patients PCI, in emergency PCI treatment need to control the above risk factors, in order to obtain the ideal treatment and prognosis effect.
2021 Vol. 41 (2): 5-6 [
Abstract
] (
104
)
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7
Effect of Topiramate Tablets and Valproate on EEG in Elderly Patients With Epilepsy
Li Qiong, Wei Jianguo, Li Yihao
Objective
To investigate the effect of topiramate tablets and sodium valproate on electroencephalogram（EEG） in elderly patients with epilepsy.
Methods
A total of 78 elderly patients with epilepsy were selected as the test subjects.They were divided into a study group and a control group by using random number table,39 cases each.The control group was treated with sodium valproate,and the research group was treated with topiramate tablets.The changes in seizure frequency,duration of seizures,and EEG tests（epileptic discharge,number of leads involved） were compared before and after 3 months of treatment in the two groups.
Results
After 3 months of treatment,the frequency of seizures and duration of seizures in the two groups were lower than before treatment,and the study group was lower than the control group over the same period（both
P<
0.05）.The number of epilepsy-like discharges and the number of leads involved in the two groups were lower than before treatment,and the study group was lower than the control group over the same period（both
P<
0.05）.There was no significant difference in adverse reactions between the two groups during the treatment（both
P
>0.05）.
Conclusion
Topiramate tablets are more effective than sodium valproate in elderly patients with epilepsy,and have more obvious improvements in EEG.They are safer and are beneficial to their prognosis.
2021 Vol. 41 (2): 7-8 [
Abstract
] (
106
)
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9
Comparison of the Effect Between Modified Laparoscopic and Transabdominal Hysterectomy in the Treatment of Giant Hysteromyoma
Huang Ju, Wang Yun, Lv Jia
Objective
To compare the effect between modified laparoscopic and transabdominal hysterectomy in the treatment of giant hysteromyoma.
Methods
70 patients withgiant hysteromyoma were selected and divided into the control group and the observation group by random numbering method,with 35 patients in each group.The control group were treated with transabdominal hysterectomy,and the observation group were treated with modified laparoscopic hysterectomy.The incision length,operation time,intraoperative blood loss,success rate of surgery,postoperative exhaust time,time to get out of bed,length of hospital stayand complications were compared between the two groups.
Results
Surgeries for both groups were successfully completed.The incision length,operation time and postoperative hospital stay of the observation group were significantly shorter than those of the control group（
P<
0.01）.The intraoperative blood loss,postoperative exhaust time and time to get out of bed were also significantly less/shorter than those of the control group（
P<
0.01）.However,there was no significant difference in intraoperative or postoperative complications between the two groups（
P>
0.05）.
Conclusion
Compared with transabdominal hysterectomy,modified laparoscopic hysterectomyhas the advantages of less trauma,shorter operation time,and quicker postoperative recovery in the treatment of giant hysteromyoma.
2021 Vol. 41 (2): 9-10 [
Abstract
] (
132
)
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11
Comparative Study of Efficacy and Safety of Titanium Clip and Nylon rope in the Removal of Large Intestine Thick Pedicled Polyps Under Colonoscopy
Gao Fei, Li Caihong, Zhao Guowei
Objective
To compare the efficacy and safety of titanium clip and nylon rope in the removal of large intestine thick pedicled polyps under colonoscopy.
Methods
A total of 110 patients with large intestine thick pedicled polyps were selected and divided into control group and observation group according to the random number table method,with 55 cases in each group.Control group was treated with titanium clip under colonoscopy and observation group was treated with nylon rope under colonoscopy.The surgical efficacy was compared between the two groups,and the operative time,intraoperative blood loss,discharge time and postoperative intestinal recovery time were compared between the two groups,and the occurrence of postoperative blood loss,postoperative infection and bowel perforation were counted in the two groups.The patients were followed up at 6 months after surgery,and the recurrence of polyps was counted in the two groups.
Results
The success rate of surgery in observation group was higher than that in control group（87.27% vs 70.91%）（
P
<0.05）.The discharge time and postoperative intestinal recovery time in observation group were shorter than those in control group（
P
<0.05）.There were no significant differences in the recurrence rate of polyps at 6 months after surgery and the incidence rates of postoperative complications between the two groups（
P>
0.05）.
Conclusion
Compared with titanium clip,nylon rope for removal of large intestine thick pedicled polyps under colonoscopy can improve the success rate of surgery and shorten the hospital stay.
2021 Vol. 41 (2): 11-12 [
Abstract
] (
187
)
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13
Effect of Artificial Femoral Head Replacement on Intertrochanteric Comminuted Fracture in Elderly Patients With Severe Osteoporosis
Han Weiwei
Objective
To investigate the effect of artificial femoral head replacement on the disease data of senile severe osteoporosis intertrochanteric fracture.
Methods
60 patients were randomly divided into two groups,30 cases in the control group were treated with proximal femoral nail fixation under general anesthesia,and 30 cases in the experimental group were treated with artificial femoral head replacement under general anesthesia.The operation indexes,Harris score of hip joint and postoperative complications were compared between the two groups.
Results
There were significant differences in the indexes of the experimental group,such as longer operation time and more intraoperative blood volume,compared with the control group,the time of getting out of bed and hospitalization in the experimental group was shorter,and the difference was also significant（
P<
0.05）;Harris evaluation of 6 months and 12 months after operation in the two groups was significant The score of the experimental group was significantly higher than that of the control group（
P<
0.05）;there was no significant difference in the total incidence of postoperative complications between the two groups（
P
>0.05）.
Conclusion
Artificial femoral head replacement in the treatment of senile severe osteoporosis intertrochanteric comminuted fracture has the advantages of satisfactory improvement of hip joint function and less complications,but it has the defect of large surgical trauma.
2021 Vol. 41 (2): 13-14 [
Abstract
] (
103
)
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15
The Effect of Levosimendancombined With Mechanical Ventilation on Severe Heart Failure in ICU and Its Influence on Heart Function
Fu Wenhui, Ren Fengjiao, Zhang Zhao
Objective
To evaluate the effect of levosimendan combined with mechanical ventilation in the treatment of severe heart failure in ICU.
Methods
52 patients with severe heart failure who were admitted to the Intensive Care Unit（ICU） of our hospital from April 2018 to April 2019 were selected as the research object,26 cases each.Both groups of patients were given conventional treatment for heart failure,the control group received mechanical ventilation,and the experimental group was treated with levosimendan combined with mechanical ventilation.Before treatment and after 7 days of treatment,the changes of blood gas indexes（PaCO
2,
SaO
2,
PaO
2
）,cardiac function indexes（SV,LVESD,LVEDD,LVEF）,hemodynamic indexes（MPAP,PCWP,CO,CVP） of the two groups of patients were compared.
Results
After 7 days of intervention,the PaO
2
,SaO
2
,LVEF,SV,and CO values of the two groups of patients were significantly higher than before the intervention,and the experimental group was significantly higher than the control group at the same time（
P<
0.05）.PaCO
2
,LVESD,LVEDD,MPAP,PCWP,CVP values were significantly lower than before treatment,and the experimental group was significantly lower than the control group at the same time（
P<
0.05）.
Conclusion
Levosimendan combined with mechanical ventilation in the treatment of severe heart failure in ICU has a significant clinical effect,which can effectively improve the patient's cardiac function and is conducive to its good prognosis.
2021 Vol. 41 (2): 15-17 [
Abstract
] (
125
)
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18
Effect of Mifiscomine Combined Laparoscopic Surgery on Uterine Volume and Ovary Index Level in Patients With Uterine Adenomycinal Disease
Xu Qingli, Yan Wei
Objective
To investigate the effect of Mifiscomine combined laparoscopic surgery on uterine volume and ovary index level in patients with uterine adenomycinal disease.
Methods
The 80 cases of uterine adenomycics were treated as subjects,and with the approval of the Medical Ethics Committee,a single-blind method was used for grouping,divided into observation group（n=40）,control group（n=40）,and all patients was treated by laparoscopic surgery,based on this,the observation group was treated with Mifiscomine,Comparing the volume of the uterus,ovary index and adverse reaction symbiosis of the two groups.
Results
After treatment,the uterine volume of the observation group（103.64±15.28） cm3,retinoids[LH（7.25±2.12） IU/L],serum follicle stimulators [FSH（5.10± 1.85） IU/L],ester [E2（51.60±6.14 pg/ml ]is lower than the control group[（140.69±13.56） cm3,（15.68±3.56） IU/L,（7.48±2.35） IU/L,（56.28±6.20） pg/ml] and the difference is statistically significant（
P
<0.05）;the incidence of adverse reactions in the observation group was slightly lower than that of the control group,but the difference was not significant（
P>
0.05）.
Conclusion
Mifiscomine combined laparoscopic surgery can effectively reduce the uterine volume in patients with uterine adenomycinals,improve the level of ovarian index,and have fewer adverse reactions and higher safety.
2021 Vol. 41 (2): 18-19 [
Abstract
] (
129
)
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20
Application Value of PDCA in Shortening the Stay Time of Emergency Room in Patients With Chest Pain
Zhang Dongling, Kong Qiuyan, Tan Li, Lai Xunyao, Nong Yueting
Objective
To explore the application value of PDCA in shortening the stay time in emergency room of patients with chest pain.
Methods
The Acute Myocardial Infarction patients admitted to the emergency department in the first quarter of 2019 and the acute myocardial infarction patients managed by PDCA in the second quarter and the third quarter of 2019 were selected retrospectively,by comparing the number of people staying in the emergency room for more than 50 minutes and the length of time spent in the emergency room in three quarters,the applied value of PDCA in shortening the time spent in the emergency room for patients with chest pain was analyzed.
Results
The number of patients with emergency chest pain staying longer than 50 minutes in emergency room decreased from 25.32% in the first quarter to 18.62% in the second quarter and 12% in the third quarter（
P
<0.05）,pDCA decreased to 55.4±6.5 min in the second quarter and 49.3±2.3 min in the Third Quarter（
P
<0.05）.
Conclusion
PDCA can shorten the stay time in emergency room of patients with chest pain.
2021 Vol. 41 (2): 20-21 [
Abstract
] (
128
)
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22
Analysis of Prognosis of Patients With Hysteromyoma Treated By Laparoscopic Surgery
Wu Xiaojin, Deng Zisong, Chen Xiaoqing
Objective
To investigate the prognosis of patients with uterine fibroids treated by laparoscopic surgery.
Methods
A total of 66 patients with uterine fibroids were retrospectively selected and divided into observation group and control group,including 42 patients in the observation group and 24 patients in the control group.Operation indexes,ovarian function,complications and recurrence rates were compared between the two groups.
Results
The operation time of the observation group was longer than that of the control group,but the time of first anal exhaust,activity time of getting out of bed and observation time of staying in hospital was shorter than that of the control group,and the amount of blood consumed by the operation was less than that of the control group（
P<
0.05）.The total incidence of complications in the observation group was lower than that in the control group（
P<
0.05）.After postoperative follow-up,the SF-36 score in both groups increased,and the increase in the observation group was greater than that in the control group（
P<
0.05）.
Conclusion
Laparoscopic surgery has the advantages of less trauma,faster postoperative recovery and fewer postoperative complications,which is beneficial to accelerate the rehabilitation process of patients.
2021 Vol. 41 (2): 22-23 [
Abstract
] (
131
)
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24
To Explore the Risk Factors of Mycoplasma Pneumoniae Pneumonia With Respiratory Syncytial Virus Infection and Adenovirus Infection
Dai Jiazhe, Yang Dongfu, Chen Zhensong
Objective
To analyze the main risk factors of respiratory syncytial virus infection and adenovirus infection in children with Mycoplasma pneumoniae pneumonia.
Methods
A total of 40 children with Mycoplasma pneumoniae pneumonia（MPP） were selected for study.Among them,20 patients with respiratory syncytial virus infection（RSV） were selected as group A.Another 20 cases of adenovirus（ADV） infection,as group B,analyzed the main risk factors of RSP and ADV in children with MPP by multivariate regression analysis.
Results
After a single factor analysis,it was found that 6 months to 2 years old,time of onset,repeated respiratory infections,bronchial asthma,and low immunity were the influencing factors of RSV in children in group A;Bronchial asthma and immunodeficiency are the influencing factors of ADV in group B children,
P<
0.05,and there are statistical differences between each factor.Multivariate analysis found that between 6 months and 2 years old,nutritional anemia and immunodeficiency are independent risk factors for RSV in children in group A,and nutritional anemia and immunodeficiency are children in group B Combine the independent risk factors of ADV.
Conclusion
Children with MPP are more likely to be complicated with other infectious diseases,of which age is 6 months to 2 years old,accompanied by nutritional anemia and immune deficiency are the main risk factors.Therefore,in the future clinical treatment,children with MPP with the above symptoms should pay more attention to,and a series of preventive measures can be formulated according to the found risk factors to prevent multiple infections.
2021 Vol. 41 (2): 24-25 [
Abstract
] (
133
)
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26
Effect of Naikan Therapy Combined With Duloxetine on Clinical Efficacy and Social Function of Patients With Depression
Duan Na, Zhang Lvfeng, Wang Chunfang
Objective
To investigate the clinical effect of Naikan therapy combined with duloxetine on clinical efficacy and social function of patients with depression.
Methods
68 patients with depression treated were selected as test subjects,and they were divided into study group and control group with 34 cases each according to the random number table.Patients in the control group were treated with duloxetine only,and the study group was treated with Naikan therapy on the basis.Before and after 4 weeks of treatment,the subjective sleep quality（PSQI,SDS,SAS） and social function improvement（SFRS） of patients in both groups were compared.
Results
After 4 weeks of treatment,the PSQI,SDS,SAS,and SFRS indexes of the two groups were significantly lower than before treatment,and the study group was lower than the control group at the same time（
P<
0.05）.
Conclusion
Duloxetine combined with Naikan therapy can improve subjective sleep quality and clinical symptoms in patients with depression,and significantly improve social function.
2021 Vol. 41 (2): 26-28 [
Abstract
] (
113
)
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192
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29
Comparison of the Efficacy of Candisatan and Fluoroquine in the Treatment of Migraines
Yang Lina
Objective
To explore the efficacy of candisatan and fluoroquine in the treatment of migraines.
Methods
The 100 migraine patients treated,according to the blind extraction method,divided into a control group（Fluoroquine,49 cases）,observation group（Candisatan,51 cases）,both groups were given regular treatment at the same time,comparing the clinical efficacy,migraine attacks and adverse reaction struck in both groups.
Results
After treatment,compared with the total efficiency of the control group of 81.63%,the observation group was 96.08% higher.the VAS score,the time of headache attack and the frequency of headache attack were lower than before treatment,and the observation group was lower than the control group,and the difference was statistically significant（
P<
0.05）.compared with 16.33% of the adverse reactions in the control group,and the observation group was slightly lower at 5.88%,but the difference was not statistically significant（
P>
0.05）.
Conclusion
Migraine patients use Candacetan treatment is better,can effectively shorten the frequency and seizure time of headache in patients,reduce the degree of pain,and the incidence of adverse reactions is less,high security.
2021 Vol. 41 (2): 29-30 [
Abstract
] (
177
)
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132
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31
Clinical Study on Duloxetine and Duloxetine Combined With Aripiprazole in Treatment of Depression
Wang Chunfang, Deng Fangyuan, Duan Na
Objective
To observe clinical curative effect of duloxetine and duloxetine combined with aripiprazole on depression.
Methods
78 depression patients who were admitted to the hospital were enrolled.They were divided into two groups by random number table method,39 cases in each group.The control group was given duloxetine,while observation group was given duloxetine combined with aripiprazole.After 8 weeks of observation,curative effect was compared between the two groups.The score of Hamilton Depression Scale（HAMD）,curative effect,scores of Pittsburgh Sleep Quality Index（PSQI）,Quality of Life（QOL） and treatment emergent symptom scale（TESS） after treatment were compared between the two groups.
Results
On the 2nd,4th,6th and 8th week after treatment,HAMD scores of observation group were higher than those of control group（
P
<0.05）.After treatment,efficiency rate of observation group was higher than that of control group（
P
<0.05）.PSQI of observation group was significantly lower than that of control group,while QOL was significantly higher than that of control group（
P
<0.05）.There was no significant difference in TESS score between the two groups（
P>
0.05）.
Conclusion
The curative effect of duloxetine combined with aripiprazole is better on depression,which can effectively improve their sleep and quality of life,without significant adverse reactions.
2021 Vol. 41 (2): 31-32 [
Abstract
] (
192
)
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33
Investigation and Analysis of the Current Status of Dietary Nutrition Intervention For Type 2 Diabetes in Shanzhou District,Sanmenxia
Li Yongbo
Objective
To investigate the current status of dietary nutrition interventions for patients with type 2 diabetes in Shanzhou District,Sanmenxia City,and to analyze the effects of dietary nutrition interventions on the treatment of patients with type 2 diabetes.
Methods
280 patients with type 2 diabetes were selected as the research object and divided into control group and observation group.The control group was given routine hypoglycemic drug treatment and diabetes diet guidance.On the basis of the control group,the observation group was given dietary nutrition intervention to compare the general nutrition indicators and clinical indicators of the two groups before and after treatment.The general nutritional indicators and clinical indicators before and after treatment were compared between the two groups.
Results
There was no significant difference in triceps skinfold thickness,waist circumference,BMI and DBP before treatment between the two groups（
P>
0.05）.After treatment,the triceps skinfold thickness,waist circumference,BMI and DBP of both groups were lower than before treatment（
P<
0.05）,and the triceps skinfold thickness,waist circumference,BMI and DBP of the observation group after treatment were significantly lower than that of the control group.The difference was statistically significant（
P<
0.05）.There was no significant difference in FBG,2hBG,FIns,2hIns,HOMA insulin IR and HbAlc in the glucose metabolism levels of the two groups before clinical treatment（
P>
0.05）.After treatment,FBG,2hBG,FIns,2hIns,IR and HbAlc were lower than before treatment（
P<
0.05）,and FBG,2hBG,FIns,2hIns,IR and HbAlc were significantly lower in the observation group after treatment compared with the control group ,The difference is statistically significant（
P<
0.05）.Before treatment,the clinical indicators of TG and TC were not significantly different（
P<
0.05）.After treatment,TG and TC of both groups were lower than before treatment（
P<
0.05）.After treatment,the TG and TC of the observation group were significantly lower than those of the control group,and the difference was statistically significant（
P<
0.05）.
Conclusion
Type 2 diabetes with dietary nutrition intervention on conventional drug therapy and diabetic diet guidance can effectively reduce body mass,stabilize the control of glucose metabolism index and lipid metabolism index,and has excellent therapeutic effect.
2021 Vol. 41 (2): 33-35 [
Abstract
] (
115
)
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129
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36
Effects of Intravitreal Injection of Ranibizumab Combined With Complex Trabeculectomy on Intraocular Pressure Control in Patients With Advanced Neovascular Glaucoma
Wang Yafei, Zhao Xingxing, Li Jie
Objective
To analyze the effects of intravitreal injection of ranibizumab combined with complex trabeculectomy on intraocular pressure in patients with advanced neovascular glaucoma.
Methods
The clinical data of 67 patients with neovascular glaucoma in our hospital were retrospectively analyzed,and the patients were divided into observation group and control group.The changes of intraocular pressure,iris neovascularization and recurrence were observed before and after treatment,and the occurrence of complications were compared.
Results
There was no statistically significant difference in the intraocular pressure with（13.26 ± 2.13） mmHg in observation group compared with（14.22 ± 3.01） mmHg in control group at 1 week after treatment（
P>
0.05）.The intraocular pressure values in observation group at 1 month,3 months and 6 months of review were（14.56 ± 3.82） mmHg,（15.26 ± 3.13） mmHg and（16.11 ± 3.45） mmHg,which were lower than those in control group with（19.01 ± 3.21） mmHg,（23.55 ± 5.24） mmHg and（27.21 ± 4.28） mmHg（
P
<0.05）.The recession rate of iris neovascularization in observation group within 1 month was better than that in control group,and the recurrence rate within 6 months was lower than that in control group（5.00% vs 26.67%）（
P
<0.05）.The occurrence of complications were basically the same in both groups（
P>
0.05）.
Conclusion
Intravitreal injection of ranibizumab combined with complex trabeculectomy is effective among patients with neovascular glaucoma,and it can safely and effectively reduce intraocular pressure.
2021 Vol. 41 (2): 36-37 [
Abstract
] (
133
)
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144
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38
Analysis of the Effect of Single-Line Gingival Removal Combined With Expasyl in the Treatment of Caries in the Subgingival Root Surface of the Elderly
Zeng Jing, Huang Wenbo, Zeng Qing
Objective
To explore the effect of single-line gingival removal combined with Expasyl in the treatment of caries in the subgingival root surface of the elderly.
Methods
A total of 258 elderly patients with anterior subgingival root caries diagnosed were selected and divided into three groups according to different schemes.Group I（81 cases,132 tablets,using the single-line gingival plan）,Group II（87 cases,143 tablets,using the Expasyl program）,Group III（90 cases,146 tablets,using the single-linegingival joint Expasyl）.Compare the three groups of gingival time,gingival pain degree,whether gingival bleeding,gingival excellent rate and improved USPHS standards and so on.
Results
After treatment,the gingival drainage time and gingival pain in group II were significantly shorter/lower than those in groups I and III,and the bleeding rate was significantly lower than that in groups I and III,the difference was statistically significant（
P<
0.05）.The excellent and good rate of gingival removal in group III was 97.26%,which was significantly higher than that in group I,84.84% and group II,86.71%.The complex restoration of group III,edge coloring,pulp reaction,edge suitability,gingival reaction,etc.were significantly better than those of groups I and II（
P<
0.05）.There was no significant difference in the new defects and secondary cariesamong the three groups（
P>
0.05）.
Conclusion
The three gingival removal methods can achieve good gingival removal effect in the treatment of anterior subgingival root caries in the elderly.The Expasyl regimen has low pain and less bleeding,and it is suitable for elderly people who cannot cooperate for a long time.The single-line gingival removal combined gingival ointment scheme has a low rate of restoration loss,little gum and pulp reaction,and the best clinical effect.
2021 Vol. 41 (2): 38-40 [
Abstract
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120
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41
Observation on Curative Effect of Ultrasound-Guided Percutaneous Puncture Catheter Drainage on PPC and Recurrence rate
Xie Caifeng, Liu Wei, Wang Yu
Objective
To study curative effect of ultrasound-guided percutaneous puncture catheter drainage（PPCD）on the elderly with pancreatic pseudocysts（PPC）and recurrence rate.
Methods
The clinical data of 50 elderly PPC patients who were diagnosed were retrospectively analyzed.According to different treatment methods,they were divided into study group（28 cases）and control group（22 cases）.The former underwent ultrasound-guided PPCD,while the latter underwent routine open drainage.The curative effect,perioperative indexes and complications were compared between the two groups.Follow-up was performed after six months of surgery.The recurrence situations of patients were statistically analyzed.
Results
The operation time and hospitalization time in study group were significantly shorter than those in control group（
P
<0.05）.There was no significant difference in recurrence rates between the two groups（
P>
0.05）.The incidence of complications in study group was significantly lower than that in control group（7.14% vs 36.36%,
P
<0.05）.The curative effect of study group was significantly better than that of control group（96.43% vs 77.27,
P
<0.05）.
Conclusion
The application of ultrasound-guided PPCD in elderly PPC patients can significantly shorten operation time and recovery time,improve curative effect,reduce complications,with low recurrence rate.
2021 Vol. 41 (2): 41-42 [
Abstract
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124
)
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43
Efficacy of Ulcer Decoction Combined With Rabeprazole in the Treatment of hp-Associated Duodenal Ulcer and Its Effect on Serum NF- B and TNF-in Patients
Li Jing
Objective
To investigate the efficacy of ulcer decoction combined with rabeprazole in the treatment of hp-associated duodenal ulcer and its effect on the serum Nuclear factor kappa-B（NF-B） and Tumor necrosis factor-（TNF-）.
Methods
According to the random number table method,96 cases of hpa-associated duodenal ulcer patients admitted to the department of gastroenterology of our hospital were divided into control group and observation group,48 cases each.The control group was treated with rabeprazole enteric-coated tablets combined with clarithromycin tablets and amoxicillin capsules,and the observation group was treated with ulcer decoction based on rabeprazole enteric-coated tablets combined with clarithromycin tablets and amoxicillin capsules.Serum levels of NF-B and TNF- were compared before and after treatment.
Results
the total clinical effective rate of the observation group was 93.75%,significantly higher than that of the control group（77.08%）（
P<
0.05）.after treatment,the serum levels of TNF- and NF- B in both groups were significantly lower than those before treatment（
P<
0.05）,and the serum levels of the above two indicators in the observation group were significantly lower than those in the control group（
P<
0.05）.the eradication rate of Hp in the observation group was 93.75%,significantly higher than that in the control group（72.92%）（
P<
0.05）.The recurrence rate of the observation group was 10.42%,significantly lower than that of the control group（18.75%）（
P<
0.05）.
Conclusion
Ulcer decoction combined with rabeprazole is effective in the treatment of hp-associated duodenal ulcer,which can effectively eradicate Hp,reduce the rate of disease recurrence,and reduce the serum levels of NF- B and TNF- in patients.
2021 Vol. 41 (2): 43-44 [
Abstract
] (
139
)
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