Abstract：Objective To investigate the effect of salvianolate on cardiac function and safety in patients with stable angina pectoris. Methods 88 patients with stable angina pectoris were selected,and they were divided into two groups according to the random number table method,44 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with salvianolate.Angina pectoris attack,cardiac function,vascular endothelial function and adverse reactions were compared between the two groups. Results After treatment,the frequency of angina pectoris attack in the observation group was（1.06±0.21）times / week,which was less than that of the control group,and the attack time was（2.01±0.41）min,which was shorter than that of the control group（P<0.05）;after treatment,the left ventricular ejection fraction（LVEF）,cardiac output（CO）,E peak/A peak（E/A）of ventricular diastolic index in the observation group were（54.69±5.18）%,（5.08±0.89）L/min,（1.18±0.05）,which was higher than that of the control group（P<0.05）;After treatment,the nitric oxide（NO）of the observation group was（7.16±1.03）μmol/L,which was higher than that of the control group,and the endothelin-1（ET-1）was（53.62±5.24）ng/L,which was lower than that of the control group（P<0.05）;there was no serious adverse reaction in both groups. Conclusion Salvianolate can reduce the frequency of angina pectoris in patients with stable angina pectoris,shorten the duration,improve vascular endothelial function,and promote the recovery of cardiac function,which is safe and reliable.
王合望. 丹参多酚酸盐注射液辅治对稳定性心绞痛患者心绞痛发作及心功能指标的影响[J]. 哈尔滨医药, 2021, 41(6): 11-13.
Wang Hewang. Effect of Salvia Polyphenolic Injection on Angina Pectoris Attack and Cardiac Function Indexes in Patients With Stable Angina Pectoris. journal1, 2021, 41(6): 11-13.
2021, Vol. 41 
