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2021 Vol. 41, No. 3
Published: 2021-06-25
1
Correlation Analysis of Thinprep Cytologic Test Between Cervical Lesions and HPV Infection in Women in Zhongshan City
Fu Lihua, Luo Xiaowan, Luo Yanyan, Sun Jiaxing, Lin Yuye
Objective
To explore the correlation between high-risk HPV infection,thinprep cytology test detection and cervical lesions in women in Zhongshan city.
Methods
2756 HPV positive patients were selected as the study subjects,which all patients underwent thinprep cytology test,HPV and pathological examination.The pathological examination was used as the gold standard to study the relationship among the three.
Results
The positive rate of cervical lesions detected by TCT was 13.90%,and there were 112 patients with high-risk HPV16/18 type accounting for 29.24%.There were significant difference in the infection rate of high-risk HPV detected by TCT in each group(
P<
0.05).The high-risk HPV infection rate in HSIL group was higher than that in LSIL group(
P<
0.05).The positive rates of TCT detection for different cervical lesions from high to low were cervical cancer,HSIL,LSIL,cervicitis and no abnormal(
P<
0.05).The positive coincidence rate of TCT and high-risk HPV combined test was higher than that of single TCT or high-risk HPV test(
P<
0.05).The positive coincidence rates of single TCT test,high-risk HPV test and combined test for different cervical lesions from high to low were cervical cancer,HSIL and LSIL(
P<
0.05).
Conclusion
Persistent infection of high-risk HPV is the main pathogenic factor for cervical cancer and cervical lesions,and the combined detection of TCT and high-risk HPV is conducive to the early diagnosis of cervical lesions.
2021 Vol. 41 (3): 1-2 [
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117
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3
Analysis of Efficacy of Metoprolol Combined With Xinmailong Injection in the Treatment of Patients With Chronic Heart Failure
Wang Lufang, Chang Chao, Zhao Yali
Objective
To explore the therapeutic effect of Metoprolol combined with Xinmailong injection in patients with chronic heart failure.
Methods
60 patients with chronic heart failure were randomly divided into a control group(n=30)and an observation group(n=30),both groups were given routine treatment,on this basis,the control group was received Metoprolol treatment,the observation group was given Metoprolol combined with Xinmailong injection,the course was lasted for 15 days.The levels of cardiac function indexes(LVEDD,LVEF),N-terminal pro-brain natriuretic peptide(NT-proBNP)and high-sensitivity troponin(cTnI)levels before and 15 days after treatment were compared between the two groups.
Results
After 15 days of treatment,the LVEF of both groups increased compared with that before treatment,while LVEDD decreased compared with before treatment.The LVEF of the observation group was higher than that of the control group,and the LVEDD was lower than the control group,the difference was statistically significant(
P<
0.05).After 15 days of treatment,the levels of cTnI and NT-proBNP in the two groups decreased,and the observation group was lower than the control group,the difference was statistically significant(
P<
0.05).
Conclusion
Metoprolol combined with Xinmailong injection has a good effect on patients with chronic heart failure,which can effectively improve the heart function of patients and promote the recovery of myocardium.It is worthy of clinical promotion.
2021 Vol. 41 (3): 3-5 [
Abstract
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116
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6
Analysis of First aid Effect of Urapidil Hydrochloride on Patients With Hypertensive Crisis
LI Cuiying, WU Jinhai
Objective
To explore the effect of urapidil hydrochloride on patients with hypertensive crisis.
Methods
86 patients with hypertensive crisis who were received were selected and divided into an observation group and a control group according to the blind sampling method,with 43 cases each.The control group was treated with sodium nitroprusside,and the observation group was treated with urapidil hydrochloride.The changes at 10,30 and 60 minutes after using drugs in blood pressure [systolic blood pressure(SBP),diastolic blood pressure(DBP)],heart rate(HR),and clinical efficacy after 60 minutes of medication were compared between the two groups.
Results
Before treatment,there was no statistically significant difference in SBP,DBP,and HR between the two groups(
P>
0.05);10min,30min,and 60min after medication,compared with before medication,the SBP,DBP,and HR of the two groups were reduced,and compared with the control group of the same period,the observation group was lower and the difference was statistically significant(
P<
0.05);60 minutes after medication,the total effective rate of treatment in the observation group(97.67%)was higher than that of the control group(76.74%),the difference was statistically significant(
P<
0.05).
Conclusion
Urapidil hydrochloride has a good first-aid effect on patients with hypertensive crisis and can effectively improve their blood pressure and heart rate levels.
2021 Vol. 41 (3): 6-7 [
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156
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8
Clinical Efficacy of Glipizide Combined With Metformin Hydrochloride in the Treatment of Elderly Diabetes
Xie Weijia, Huang Liming, Huang Zhedan
Objective
To explore the clinical efficacy of glipizide combined with metformin hydrochloride in the treatment of elderly diabetes.
Methods
Select 89 elderly diabetic patients from January 2019 to January 2020 were selected and divided into control group(n=49)and combination group(n=40)according to the random number table method.The control group was treated with glipizide,while the combination group was treated with metformin hydrochloride on the basis of the control group.The changes of blood glucose index,treatment effect and adverse reaction rate before and after treatment were compared between the two groups.
Results
After treatment,the FPG,2hFPG,HbA1c and FINS of the two groups were significantly lower than before treatment,and the above indicators of the combination group were lower than those of the control group(
P<
0.05);The total effective rate of the combined group was 92.5%,which was significantly higher than the 75.51% of the control group(
P<
0.05).
Conclusion
Glipizide combined with metformin hydrochloride in the treatment of elderly diabetic patients can effectively improve the blood glucose level,blood glucose control and therapeutic effects are better than glipizide alone.
2021 Vol. 41 (3): 8-9 [
Abstract
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123
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10
Clinical Effect of Laparoscopic Gastric Perforation in Patients With Gastric Ulcer Cancer and Fungal Infection
Xu Shuo, Xu Fajie, Zhang Mingchu
Objective
To investigate the efficacy and safety of laparoscopic gastric perforation repair in patients with gastric ulcer(GU)cancer and fungal infection.
Methods
A total of 90 patients with GU and fungal infections were selected.The random number table method was used to divide them into observation group and control group,each with 45 cases.The control group received radical gastrectomy and the observation group received laparoscopic repair of gastric perforation.Compare the efficacy,clinical treatment-related indicators and the incidence of postoperative complications in the two groups.
Results
The total clinical effective rate of the observation group was 93.33%,which was significantly higher than 77.78% of the control group(
P<
0.05).The operation time,intraoperative blood loss,postoperative anal exhaust time,bowel sound recovery time,hospitalization time,1w postoperative fungal detection rate,and VAS of the observation group were significantly lower than those of the control group(
P<
0.05).The incidence of postoperative complications in the observation group was 4.44%,which was significantly lower than that in the control group(31.11%).The difference was statistically significant(
P<
0.05).
Conclusion
Laparoscopic gastric perforation repair for patients with GU cancer and fungal infection can reduce intraoperative blood loss,shorten operation time,anal exhaust time,bowel sound recovery time and hospitalization time,reduce pain,and have significant effect and high safety,which is worthy of clinical promotion.
2021 Vol. 41 (3): 10-11 [
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134
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12
Study on the Efficacy of Oxaliplatin Combined With Chemotherapy in Colon Cancer
Zhu Xiuping
Objective
To carry out oxaliplatin combined with chemotherapy in patients with colon cancer,and analyze the clinical effect of this method.
Methods
A total of 78 patients with colon cancer were searched.The patients were all treated with oxaliplatin + 5-fluorouracil + calcium leucovorin,and the clinical application of this treatment was analyzed..
Results
The treatment effect of the patients increased significantly,TNF-α decreased,IL-2 decreased,and the incidence of adverse reactions was low,especially the decrease of white blood cells and stomatitis.
Conclusion
Oxaliplatin combined with chemotherapy is effective and safe in treating colon cancer.
2021 Vol. 41 (3): 12-13 [
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146
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14
Analysis of Diagnostic Value of B-Ultrasound in Placental Abruption of Different Severity
Zhao Shuiyu, Wei Qing, Xuan Qingxia
Objective
To investigate the diagnostic value of B-ultrasound in placental abruption of different severity.
Methods
63 cases with prenatal diagnosis of placental abruption were retrospectively analyzed,and the data of puerperae were confirmed after delivery.According to the severity of placental abruption,they were divided into grade I,grade II and grade III by Sher method,and they were compared with the B-ultrasound diagnosis results.The ultrasound characteristics of placental abruption of different severity were analyzed.
Results
47 cases of placental abruption were diagnosed by B-ultrasound,and the detection rate was 74.60% and the accuracy rate was 55.32%(26/47),including 7 cases of mild(grade I)placental abruption and 19 cases of moderate-to-severe(grade II-III)placental abruption.Among patients with grade I placental abruption,there was no blood accumulation behind the placenta and there was no obvious change in placental shape.Among patients with grade II placental abruption,the placenta was thickened in the separation area and protruded toward the amniotic cavity.Among patients with grade III placental abruption,there was messy hematoma internal echo between the placenta and uterine wall and poor sound transmission in amniotic fluid,and there were low floating echoes and clumps.
Conclusion
B-ultrasound of different degrees of placental abruption is different.B-ultrasound can be used in the diagnosis of placental abruption and provide sonograms for clinical reference,but other examinations are needed.
2021 Vol. 41 (3): 14-15 [
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136
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16
Application of Prophylactic Usage of Danshen Chuanxiongqin Combined with Low-molecular Weight Heparin Calcium in Deep Vein Thrombosis of Patients After Femoral Neck Fracture Surgery
Pan Hongzhao, Pan Hongliang, Zheng Chenping, Jiang Yunheng
Objective
To observe the application effect of prophylactic usage of Danshen Chuanxiongqin combined with low-molecular weight heparin(LMWH)calcium in deep vein thrombosis(DVT)of patients after femoral neck fracture surgery.
Methods
Sixty patients who were treated and underwent femoral neck fracture surgery were enrolled.They were divided into observation group(Danshen Chuanxiongqin combined with LMWH calcium)and control group(LMWH calcium)by random number table method,30 cases in each group.The occurrence of postoperative DVT,changes of related indexes,and adverse reactions in both groups were observed.
Results
After treatment,the difference in incidence of DVT between observation group and control group was not statistically significant(3.33% vs 16.67%)(
P>
0.05).The improvement of coagulation indexes in observation group was better than that in control group(
P<
0.05),and improvement of inflammatory factors was better than that in control group(
P<
0.05).There was no adverse reactions in either group.
Conclusion
The application of Danshen Chuanxiongqin combined with LMWH calcium can effectively reduce coagulation risk in patients undergoing femoral neck fracture surgery,and reduce inflammation level,with good safety.
2021 Vol. 41 (3): 16-17 [
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160
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18
Feasibility of Colposcopy-Assisted Enucleation in Pregnant Patients With Cervical Polyps and Its Effects on Maternal-Infant Outcomes
Xiao Sa, Miao Hongyan, Fan Huimin
Objective
To analyze the feasibility of colposcopy-assisted enucleation in pregnantpatients withcervical polyps and to observe the effects on maternal-infant outcomes.
Methods
The clinical data of 94 patients with pregnancy with cervical polyps in our hospital were retrospectively analyzed.Those who underwent colposcopy-assisted enucleation during pregnancy were included in observation group(n=50),and those who underwent conservative treatment were included in control group(n=44).The perioperative basic situationwas analyzedin observation group,and the adverse pregnancy outcomes,delivery modes and perinatal outcomes were compared between the two groups.
Results
In observation group,the operative time was(32.34±12.56)h,and the intraoperative blood loss was(48.24±15.24)ml,and the postoperative bleeding duration was(3.24±1.56)h.Within 3d after surgery,there was 1 case(1.82%)of continuous vaginal bleeding and 1 case(2.27%)of postoperative infection.The vaginal delivery rate,adverse pregnancy outcomes,birth weight of perinatal infants and Apgar score at 5min after birth in observation group were slightly higher than those in control group(
P>
0.05).
Conclusion
Colposcopy-assisted enucleation for patients with pregnancy withcervical polyps has little effects on delivery modes,adverse pregnancy outcomes and perinatal outcomes.The operation has good safety and is suitable for clinical application.
2021 Vol. 41 (3): 18-20 [
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125
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21
Effect of Peritoneal Dialysis Combined With Hemodialysis on Cardiac Function and Nutritional Status in Patients With Uremia
Chen Jinbin, Li Mingjing, Jin Shasha, Xu Xiaozhu
Objective
To observe the effect of peritoneal dialysis(PD)combined with hemodialysis(HD)on cardiac function and nutritional status in patients with uremia.
Methods
98 patients with uremia were selected and divided into control group and observation group by the random numbering method,49 cases in each group.The control group were treated with PD only,and the observation group were treated with PD combined with HD.The changes of cardiac function and nutritional status in the two groups before and after treatment were compared.
Results
After treatment,the hemoglobin(Hb)and albumin(Alb)levels and left ventricular ejection fraction(LVEF)in the observation group were significantly higher than those in the control group(
P<
0.05).
Conclusion
PD combined with HD can improve the cardiac function and nutritional status in patients with uremia.
2021 Vol. 41 (3): 21-22 [
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124
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23
Minimally Invasive Drainage in The Treatment of Chronic Subdural Hematoma After Traumatic Brain Injury
Zhang Chaochao
Objective
To investigate the clinical effect of minimally invasive drainage in the treatment of chronic subdural hematoma after brain injury,and to analyze the influence of complications.
Methods
82 cases of patients with chronic subdural hematoma of brain injury were treated in our hospital from April 2016 to April 2020.They were randomly divided into two groups,the control group and the observation group.The control group was treated with drilling and drainage,and the observation group was treated with minimally invasive drainage.The clinical efficacy and the incidence of complications of all patients were observed and compared.
Results
all patients were reexamined by cranial CT on the 5th day after operation.The residual amount of hematoma,operation time and hospitalization time of the observation group were higher than those of the control group,and the Glasgow Coma index(GCS)score of the patients was significantly higher than that of the control group.After 3 months of follow-up,the clinical symptoms of subdural hematoma of all patients were eliminated.In terms of complications,the incidence of complications in the observation group was only 4.88%,which was significantly lower than 26.83% in the control group.
Conclusion
in the treatment of chronic subdural hematoma after brain injury,the effect of minimally invasive drainage is more significant than that of drilling drainage,which is helpful to prevent the increase of postoperative complications.
2021 Vol. 41 (3): 23-24 [
Abstract
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128
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25
Effect of Laparoscopic Combined Therapy TO Induce Infertility and Its Effect on Sex Hormone Levels
Zhu Mengmeng, Shen Rumeng, Li Hui
Objective
To explore the effect of hysteroscopy combined with treatment of tubal obstruction(TO)in infertility and its effect on sex hormone levels.
Methods
80 patients with TO to infertility who received treatment from January 2019 to December 2019 The study subjects were divided into a control group and an observation group according to the order of admission of the patients.Each group had 40 patients.The control group was treated with hysteroscopy and the observation group was treated with hysteroscopy.The treatment effects of the two groups were compared.Indicators of sex hormone levels.
Results
The treatment effect of the observation group was better and the sex hormone level index was better.There was a significant difference between the two groups,which was statistically significant(
P<
0.05).
Conclusion
Hysteroscopy combined with treatment of tubal obstruction(TO)-induced infertility has a positive effect on the level of sex hormones and can effectively improve the level of sex hormones in patients.The effect of treatment of infertility is better,and it is worthy of clinical promotion.
2021 Vol. 41 (3): 25-26 [
Abstract
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135
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27
Correlation Between Color Doppler Ultrasound Blood Flow Parameters and Pregnancy Outcome in Scar Uterus
Luo Xiangyun, Hu Jiao, Gu Xiaoshan
Objective
To study the correlation between color Doppler ultrasound blood flow parameters and pregnancy outcome in scar uterus.
Methods
62 cases of uterine scar pregnancy again,as the observation group,and 60 cases of uterine scar pregnancy again as the control group,using color doppler ultrasonic detection of uterine artery(UTA)pulse index(PI),resistance index(RI),systolic/diastolic peak flow velocity(S/D),and follow-up the pregnancy outcome,wai begat outcome can be divided into adverse pregnancy outcome group(n=35)and normal pregnancy outcome group(n=25),Meanwhile,the correlation between PI,RI,S/D and pregnancy outcome of UTA was analyzed.
Results
The UTA values of PI,RI and S/D in the observation group were higher than those in the control group(
P<
0.05).The UTA values of PI,RI and S/D in the adverse pregnancy outcome group were higher than those in the normal pregnancy outcome group(
P<
0.05).Birth weight,PH of umbilical artery,Apgar score and placental weight in the observation group were lower than those in the control group(
P<
0.05).Spearman correlation analysis showed that UTA PI,RI,S/D were negatively correlated with birth weight,umbilical artery PH,Apgar score and placental weight(
P<
0.05).
Conclusion
The UTA resistance index measured by color Doppler ultrasonography in women with scar uterus repregnancy can be used to evaluate pregnancy outcome and is negatively correlated with pregnancy outcome.
2021 Vol. 41 (3): 27-28 [
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93
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29
Analysis of the Difference Between Pathological Stage and Clinical Stage of Cervical Cancer and the Risk Factors Influencing Lymph Node Metastasis
Liu Yingxia, Huang Zhuoya, Zhong Ming, Chen Mingquan, Zhao Wenli
Objective
To explore the difference between pathological and clinical stages of cervical cancer and the risk factors affecting lymph node metastasis,so as to provide scientific theories for clinical reference.
Methods
The clinical data of 80 patients with cervical cancer were retrospectively analyzed.The pathological stage and clinical stage of the patients were analyzed and compared,and the risk factors of lymph node metastasis were also understood.
Results
The clinical staging Ⅰ,Ⅰ B,A and B Ⅱ Ⅱ coincidence rate was 66.67%(8/12),62.50%(20/32),57.14%(12/21),53.33%(8/15),clinical staging total coincidence rate was 60.00%(48/80).Univariate analysis showed that there were statistically significant differences in clinical stage,chemotherapy,depth of muscular layer infiltration,periuterine tissue infiltration,and tumor diameter with or without lymph node metastasis(
P<
0.05).Logistic multivariate analysis showed that high clinical stage,chemotherapy,muscular layer infiltration depth>1/2 muscular layer,periuterine tissue infiltration,and tumor diameter ≥4cm were independent risk factors for lymph node metastasis(
P<
0.01).
Conclusion
In the stage of cervical cancer,the coincidence rate of clinical stage is lower than that of pathological stage.Clinical stage,chemotherapy,depth of muscle layer infiltration,invasion of parietal tissue and tumor diameter are risk factors for lymph node metastasis.
2021 Vol. 41 (3): 29-30 [
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160
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31
Clinical Effect Analysis of Loratadine Combined With Methylprednisolone Shock in the Treatment of Allergic Purpura in Children
Lu Sumin, Zhang Guicong, Long Lina
Objective
To investigate the clinical effect of loratadine combined with methylprednisolone shock in the treatment of children with allergic purpura.
Methods
A total of 103 children with allergic purpura were retrospectively selected and grouped according to different drug administration.Forty-nine children treated with loratadine alone were included in the single group,and 54 children treated with loratadine combined with methylprednisone were included in the combined group.The clinical efficacy and the time of disappearance of clinical symptoms were compared between the two groups.
Results
The total effective rate of the combined drug group was higher than that of the single drug group,(
P<
0.05).The duration of clinical symptoms in the combined group was shorter than that in the single group,(
P<
0.05).
Conclusion
Loratadine combined with methylprednisolone shock is effective in treating children with allergic purpura and can effectively relieve the clinical symptoms of children.
2021 Vol. 41 (3): 31-32 [
Abstract
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116
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33
Observation on Effects of Azithromycin Combined With Gamma Globulin in the Treatment of Pertussis in Children
Wang Xiaofei, Wang Kaiping, Wang Yan
Objective
To study and observe the effects of azithromycin(AZM)combined with human gamma globulin(HGG)in the treatment of pertussis in children.
Methods
Totally 78 children patients with pertussis admitted to our hospital from January 2017 to December 2019 were randomly divided into single group(n=39,treated with AZM)and combined group(n=39,treated with AZM combined with HGG).After 5 d of treatment,differences in disappearance time of spastic cough symptoms,disappearance time of crow-like inspiratory roar and hospital stay were compared between the two groups.The lung function indexes [time to peak ratio(TPTEF/TE),peak volume ratio(VPEF/VE)] were compared before treatment and after 5d of treatment.The occurrence of drug side effects were analyzed in the two groups during the course of treatment.
Results
The disappearance time of spastic cough,disappearance time of crow-like inspiratory roar and hospital stay in combined group were significantly shorter than those in single group(
P<
0.05).After 5 d of treatment,the levels of TPTEF/TE and VPEF/VE in the two groups were significantly higher than those before treatment,and the levels in combined group were significantly higher than those in single group at the same time point(
P<
0.05).During the course of treatment,there were no significant differences in the drug side effects between the two groups(
P>
0.05).
Conclusion
AZM combined with HGG has a significant effect in treating pertussis in children,and it can promote the disappearance of symptoms,and does not significantly increase the incidence rates of drug side effects.Thus it is suitable for popularization and application.
2021 Vol. 41 (3): 33-34 [
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103
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35
Effects of Total Arthroscopic and Arthroscopic Assisted Small Incision Rotator Cuff Repair on Postoperative Pain Level in Patients With Rotator Cuff Tear
Gao Xu
Objective
To observe the effects of total arthroscopic and arthroscopic assisted smallincision rotator cuff repair on postoperative pain level in patients with rotator cuff tear.
Methods
Totally 64 patients with rotator cuff tear in our hospital were selected as the research subjects,and they were divided into experimental group and control group according to the random number table method,with 32 cases in each group.Patients in experimental group received all-arthroscopic rotator cuff repair,and patients in control group received arthroscopicassisted small incision rotator cuff repair.The changes of shoulder joint function [Simple Shoulder Test(SST),Constant Shoulder Joint Score System] and muscle strength were observed in the two groups before surgery and at 6 months after surgery,and the differences in perioperative status were compared between the two groups.
Results
At 6 months after surgery,the SST,Constant score and muscle strength grades of abduction,external rotation and internal rotation in the two groups were significantly higher than those before surgery,and the scores in experimental group were significantly higher than those in control group at the same time point(all
P<
0.05).There were no statistically significant differences in the surgical time,blood loss,number of implanted anchors,postoperative hospital stay and VAS score at 24h after surgery between the two groups(all
P>
0.05).
Conclusion
Total arthroscopic and arthroscopic assisted small incision rotator cuff repair in patients with rotator cuff tear are similar in clinical perioperative status,and both can relieve pain,but the former one is more conducive to the recovery of shoulder joint function and muscle strength,and has higher clinical application value.
2021 Vol. 41 (3): 35-37 [
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152
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38
Clinical Value of Urine α1-MG,Urine Transferrin,Serum β2-MG and Cys-C in Early Diagnosis of Chronic Glomerulonephritis
Pan Xiao, Yang Yang
Objective
To investigate the clinical value of urine α 1-microglobulin(α 1-MG)and serum β 2-microglobulin(β 2-MG),transferrin(TRF)and cystatin(Cys)- C in the early diagnosis of chronic glomerulonephritis.
Methods
95 patients with chronic glomerulonephritis were divided into three groups according to the pathological classification：group A(35 cases)with mesangial hyperplasia,group B(31 cases)with capillary type and group C(29 cases)with membranous type;the control group was 32 healthy people in our hospital from June 2020 to September 2020.The levels of urine α1-MG and serum β2-MG,TRF and Cys-C were detected and compared between the two groups.
Results
Compared with the control group,the levels of urine α 1-mg,serum TRF,serum β 2-mg and serum Cys-C in group A,B and C were significantly increased(
P<
0.05).Compared with group A,the levels of above detection indexes in group B and group C were increased(
P<
0.05).Compared with group A and group B,the levels of above detection indexes in group C were increased(
P<
0.05).Compared with the control group,the positive rates of detection indexes were significantly increased(
P<
0.05).There was no statistical difference between the positive rates of detection indexes in group A with group B and group B with group C(
P>
0.05).There was no statistical difference between the positive rates of detection indexes in(
P>
0.05).Compared with group A,the positive rate of detection indexes in group C was increased(
P<
0.05).
Conclusion
The levels of α - 1mg in urine and β - 2mg,TRF and Cys-C in serum of patients with chronic glomerulonephritis are abnormal.Detection of the above indicators has important clinical value in early diagnosis.
2021 Vol. 41 (3): 38-39 [
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121
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40
Observation of the Effect of Sodium Fructose Diphosphate Combined With Creatine Phosphate Acupuncture on Viral Myocarditis in Children
Yang Huimin
Objective
To observe the effect of sodium fructose diphosphate combined with creatine phosphate on children with viral myocarditis(VMC).
Methods
A total of 84 pediatric VMC children were collected as research subjects.They were divided into a control group and an observation group with 42 cases each.The control group was treated with sodium fructose diphosphate,and the observation group was treated with sodium fructose diphosphate combined with creatine phosphate.Compare the changes of myocardial injury markers(cTnI,CK-MB)and oxidative stress indicators(SOD,GSH)in the two groups of children before and after 14 days of treatment.The difference in efficacy between the two groups of children after 14 days of treatment and the difference in adverse drug reactions between the two groups of children within 14 days of treatment were compared.
Results
After 14 days of treatment,the curative effect of the observation group was significantly higher than that of the control group.The cTnI and CK-MB in the two groups of children were significantly lower than before the treatment,and the observation group was significantly lower than the control group at the same time.SOD and GSH were significantly higher than before treatment,and the observation group was significantly higher than the control group at the same time,and the difference was statistically significant(
P<
0.05).Within 14 days of treatment,there was no significant difference in the total incidence of adverse drug reactions between the two groups(
P>
0.05).
Conclusion
Sodium fructose diphosphate combined with creatine phosphate acupuncture is effective in treating children with VMC,can improve cardiac function,reduce myocardial oxidation,and has good drug safety.It is suitable for clinical popularization.
2021 Vol. 41 (3): 40-41 [
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152
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42
Analysis of Covid-19 Pneumonia Cases in Bengbu Area
Li Weiwei, Qian Feng, Sun Jingwei
Objective
To analyze the clinical data of 89 COVID-19 patients in Bengbu area to determine the severity of the patient's condition.
Methods
A retrospective study was conducted on 89 patients with common type of novel coronavirus infection pneumonia admitted to Bengbu Infectious Diseases Hospital in February 2020 as the confirmed case group.The patients were divided into mild and severe two groups,and the two groups were hospitalized Symptoms,laboratory examinations,chest CT Resultsduring the period.
Results
Mild and severe patients were relatively younger,and the clinical symptoms of severe loss of appetite and dyspnea were different,which was statistically significant(
P<
0.05);the white blood cell count,neutrophil count,and lymphocyte count of mild patients,Albumin,cystatin C,lactate dehydrogenase,microglobulin compared with severe patients,the difference was statistically significant(
P<
0.05).
Conclusion
The relevant laboratory tests and clinical symptoms of COVID-19 patients are more typical,which can be used as relevant indicators for the progress of mild patients.
2021 Vol. 41 (3): 42-44 [
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137
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163
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103
Effect Observation of Scene Simulation Teaching Method in Clinical Nursing Practice Teaching
Zhou Hongna, Zhang Guifang
Objective
To explore the application effect of scene simulation teaching method in clinical nursing practice teaching.
Methods
95 nursing interns from June 2019 to July 2020 in our hospital were selected and randomly divided into observation group(n = 47)and control group(n = 48)by random number table method.The control group was given traditional teaching mode,and the observation group was given scenario simulation teaching method.The theoretical performance,operation performance and teaching satisfaction of the two groups were compared.
Results
Before training,there was no significant difference between the two groups in theoretical and operational performance(
P>
0.05);after training,the theoretical and operational scores of the observation group were higher than those of the control group,the difference was statistically significant(
P<
0.05);the teaching satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(
P<
0.05).
Conclusion
The application of scenario simulation teaching method in clinical nursing practice teaching can help interns master theoretical knowledge and operation skills,improve teaching quality and improve teaching satisfaction,which is worthy of promotion.
2021 Vol. 41 (3): 103-104 [
Abstract
] (
97
)
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172
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105
Study on the Fine Evaluation of Mandibular Motor Ability in Patients With Voice Disorders
Dong Zhouwei, Zhang Liping
Objective
To explore the method of fine assessment of mandible motor ability in speech.
Methods
From February 2018 to June 2019,53 patients with voice disorders who came to the fourth hospital of Harbin were selected as the experimental group and 50 patients with normal pronunciation as the control group.The resonance peak when the patient pronounces vowel [a] and [i] were measured by Real time speech meter produced by taiyige company of the United States.The difference between F1(a)and F1(i)was used to reflect the opening and closing range of the mandible.The mandibular movement range and movement ability was analyzed according to the measurement results.
Results
The values of F1(a),F1(i)and △F1 in the experimental group were significantly lower than those of normal patients,and the analysis Resultswere statistically significant(
P<
0.05).
Conclusion
The measurement of vowel [a] and [i] formants can accurately reflect the motion ability and range of mandibular in the process of vocalization which is suitable for clinical application.
2021 Vol. 41 (3): 105-106 [
Abstract
] (
79
)
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170
)
123
Study on Clinical Effect and Mechanism of Ganmaiqixian Magnetic Stone Decoction Combined with Conventional Sleeping Medicine on Elderly Patients with Chronic Insomnia
Xian Zhiqiang, Zhuang Kun, Wen Nannan
Objective
To explore the clinical efficacy and mechanism of Ganmai Qixian Magnetic Stone Decoction combined with conventional sleeping drugs in elderly patients with chronic insomnia due to heart and spleen deficiency.
Methods
From September 2018 to December 2019,64 elderly patients with senile insomnia who were dialectic of TCM and Spleen Deficiency were selected as the research subjects,and were divided into observation group and control group according to the random number table method.(32 cases each).The control group was given conventional sleeping medication,and the observation group was given Ganmai Qixian Magnet Decoction on the basis of the control group.The clinical efficacy and TCM symptom scores,norepinephrine(NE)and 5- Serotonin(5-HT)levels,sleep quality.
Results
The total effective rate of clinical efficacy in the observation group was higher than that in the control group(93.75% vs 75.00%,
P<
0.05),and the total effective rate of TCM symptoms was higher than the control group(93.75% vs 71.88%,
P<
0.05);after treatment The NE level decreased and 5-HT level increased in both groups(
P<
0.05).The sleep quality in both groups was improved(
P<
0.05),and the improvement in the observation group was better than that in the control group(
P<
0.05).
Conclusion
Ganmaiqixian Magnetic Stone Decoction combined with conventional sleep medicine can effectively improve the clinical symptoms of elderly patients with chronic insomnia with heart and spleen deficiency.The effect is more obvious than that of conventional sleep medicine alone,and its mechanism may be through affecting the brain 5- The contents of HT and NE act on the sleep-wake cycle.
2021 Vol. 41 (3): 123-125 [
Abstract
] (
151
)
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145
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